Gene Symbol | CD1D |
---|---|
Entrez Gene | 912 |
Alt Symbol | CD1A, R3 |
Species | Human |
Gene Type | protein-coding |
Description | CD1d molecule |
Other Description | CD1D antigen, d polypeptide|HMC class I antigen-like glycoprotein CD1D|R3G1|T-cell surface glycoprotein CD1d|antigen-presenting glycoprotein CD1d|differentiation antigen CD1-alpha-3|thymocyte antigen CD1D |
Swissprots | Q9Y5M4 P15813 Q5W0J3 D3DVD5 Q9UMM3 |
Accessions | AAA51935 AAA59672 AAD37581 AHM95188 AHN19670 CAA33099 EAW52847 EAW52848 EAW52849 P15813 AK225996 AK310541 AK310749 BC027926 AAH27926 BX106524 J04142 AAA59673 XM_005245583 XP_005245640 XM_006711620 XP_006711683 XM_006711621 XP_006711684 XM_011510125 XP_011508427 XM_011510126 XP_011508428 XM_011510127 XP_011508429 XR_921995 XR_921996 NM_001766 NP_001757 |
Function | Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:17475845}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. |
Tissue Specificity | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
Top Pathways | Hematopoietic cell lineage, Amoebiasis |