Gene Symbol | CD6 |
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Entrez Gene | 923 |
Alt Symbol | TP120 |
Species | Human |
Gene Type | protein-coding |
Description | CD6 molecule |
Other Description | CD6 antigen|T-cell differentiation antigen CD6|T12 |
Swissprots | Q9Y4L0 Q9UMF2 A4KAD4 Q9Y4K7 P30203 Q9Y4K9 A4KAD5 Q9Y4K8 |
Accessions | AAA86417 AAA86418 AAA86419 AAC51162 AAC51163 AAL40085 AAL40086 AAL40087 AAL40088 AAL40089 EAW73917 EAW73918 EAW73919 EAW73920 EAW73921 EAW73922 EAW73923 P30203 AI657093 AK126159 AK128419 AK292704 BAF85393 AK312749 BC033755 AAH33755 BC078669 AAH78669 DB147406 DB155411 DQ786329 ABH04237 DQ786330 ABH04238 U66142 AAC51161 U66145 AAC51164 U66146 AAC51165 X60992 CAA43306 XM_006718738 XP_006718801 XM_006718739 XP_006718802 XM_006718740 XP_006718803 XM_006718741 XP_006718804 XM_011545360 XP_011543662 XM_011545361 XP_011543663 XM_011545362 XP_011543664 NM_001254750 NP_001241679 NM_001254751 NP_001241680 NM_006725 NP_006716 NR_045638 |
Function | Involved in cell adhesion. Binds to CD166. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:17371992}; Single-pass type I membrane protein {ECO:0000269|PubMed:17371992}. |
Tissue Specificity | Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. |
Top Pathways | Cell adhesion molecules (CAMs) |
CD6 CRISPR/Cas9 KO Plasmid (h) - sc-403748 from Santa Cruz Biotechnology
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CD6 HDR Plasmid (h) - sc-403748-HDR from Santa Cruz Biotechnology
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CD6 Double Nickase Plasmid (h) - sc-403748-NIC from Santa Cruz Biotechnology
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CD6 Double Nickase Plasmid (h2) - sc-403748-NIC-2 from Santa Cruz Biotechnology
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CD6 CRISPR Activation Plasmid (h) - sc-403748-ACT from Santa Cruz Biotechnology
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CD6 CRISPR Activation Plasmid (h2) - sc-403748-ACT-2 from Santa Cruz Biotechnology
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CD6 Lentiviral Activation Particles (h) - sc-403748-LAC from Santa Cruz Biotechnology
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CD6 Lentiviral Activation Particles (h2) - sc-403748-LAC-2 from Santa Cruz Biotechnology
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CD6 siRNA (h) - sc-35015 from Santa Cruz Biotechnology
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CD6 shRNA Plasmid (h) - sc-35015-SH from Santa Cruz Biotechnology
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CD6 shRNA (h) Lentiviral Particles - sc-35015-V from Santa Cruz Biotechnology
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CD6 RNAi - H00000923-R02 from Novus Biologicals
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MISSION® esiRNA - EHU063251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5742 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5742 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07607 from Sigma-Aldrich
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CD6 siRNA (Human) - CRH0651 from Cohesion Biosciences
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CD6 - MBS8240252 from MyBioSource
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shRNA set against Human CD6 (NM_006725.4) - SHH259257 from Creative biogene
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CD6 shRNA Plasmid (Human) - CHH0651 from Cohesion Biosciences
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CD6 miRNA 3'UTR clone - MiUTR3H-02165 from Creative biogene
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