ATP2A1

Gene Symbol	ATP2A1
Entrez Gene	487
Alt Symbol	ATP2A, SERCA1
Species	Human
Gene Type	protein-coding
Description	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Other Description	SR Ca(2+)-ATPase 1|calcium pump 1|calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform|endoplasmic reticulum class 1/2 Ca(2+) ATPase|sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Swissprots	O14983 A8K5J9 B3KY17 O14984
Accessions	AAB53112 AAB53113 CBG22289 CBV35450 EAW52006 O14983 AK092691 BAG52597 AK128456 BAG54679 AK291314 BAF84003 AL706356 BC037354 AAH37354 BC104452 BC104453 BC148653 AAI48654 BU737186 BX537389 CAD97631 BX537784 CAD97841 BX647365 BX647366 BX647367 BX647368 BX648544 BX649072 EF139859 EF139860 NM_001286075 NP_001273004 NM_004320 NP_004311 NM_173201 NP_775293
Function	Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity	Skeletal muscle, fast twitch muscle (type II) fibers.
Top Pathways	Alzheimer's disease, Calcium signaling pathway, Pancreatic secretion, cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SERCA1 ATPase protein fragment - ab152208 from Abcam Category Protein Source Wheat germ Species Human

ATP2A1 / SERCA1 Antibody Blocking Peptide - LS-E15519 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SERCA1 ATPase Partial Recombinant Protein - H00000487-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SERCA1 ATPase Recombinant Protein - H00000487-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ATP2A1 peptide - orb216947 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

ATP2A1 Blocking Peptide - 33R-5884 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SERCA1 Blocking Peptide - abx062278 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Rabbit

ATP2A1 / SERCA1 - H00000487-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

ATP2A1 / SERCA1 - H00000487-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ATP2A1 / SERCA1 - H00000487-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP2A1 / SERCA1 - H00000487-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP2A1 fusion protein - Ag18184 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ATP2A1 fusion protein - Ag17944 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ATP2A1, His-tagged - ATP2A1-10010H from Creative Biomart Category Protein Source E.coli Species Human

SERCA1 Blocking Peptide - CBP1084 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Rabbit

SERCA1 (D580) Peptide - BS3934P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

ATP2A1 / SERCA1 (transcript variant a) - TP314911 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ATP2A1-Antibody-C-term-Blocking-Peptide - BP4905b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ATP2A1 Peptide, Human - M34GP01141H from Creative Peptides Category Peptide Source Synthetic. Species Human

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (atp2a1), Recombinant Protein - MBS1060004 from MyBioSource Category Protein Prices $3,200.00, $3,660.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1), Recombinant Protein - MBS1044680 from MyBioSource Category Protein Prices $440.00, $580.00, $620.00, $640.00, $780.00, $835.00, $900.00, $945.00, $985.00, $1,015.00, $1,425.00, $1,425.00, $1,555.00, $1,915.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 50 µg (Yeast), 500 µg (E-Coli), 50 µg (Baculovirus), 200 µg (Yeast), 1 mg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 50 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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