Gene Symbol | LYPLAL1 |
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Entrez Gene | 127018 |
Alt Symbol | Q96AV0 |
Species | Human |
Gene Type | protein-coding |
Description | lysophospholipase-like 1 |
Other Description | lysophospholipase-like protein 1 |
Swissprots | Q7Z4A3 Q5VWZ3 Q5VWZ2 Q96AV0 A8K677 |
Accessions | CAJ42731 EAW93319 EAW93320 EAW93321 EAW93322 EAW93323 Q5VWZ2 AA417842 AA424278 AK123628 BAG53925 AK129913 AK291542 BAF84231 AK309689 AW967835 AY341430 AAQ17077 BC016711 AAH16711 BF115063 BX282451 CB851909 DA822882 HY106571 XM_006711162 XP_006711225 XM_011509182 XP_011507484 XM_011509183 XP_011507485 XM_011509184 XP_011507486 XM_011509185 XP_011507487 NM_001300769 NP_001287698 NM_001300770 NP_001287699 NM_001300771 NP_001287700 NM_001300772 NP_001287701 NM_138794 NP_620149 |
Function | Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site. {ECO:0000269|PubMed:22052940, ECO:0000269|PubMed:22399288}. |
Subcellular Location | Isoform 1: Cytoplasm, cytosol {ECO:0000269|PubMed:22399288}. |
LYPLAL1 CRISPR/Cas9 KO Plasmid (h) - sc-414290 from Santa Cruz Biotechnology
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LYPLAL1 HDR Plasmid (h) - sc-414290-HDR from Santa Cruz Biotechnology
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LYPLAL1 Double Nickase Plasmid (h) - sc-414290-NIC from Santa Cruz Biotechnology
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LYPLAL1 Double Nickase Plasmid (h2) - sc-414290-NIC-2 from Santa Cruz Biotechnology
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LYPLAL1 CRISPR Activation Plasmid (h) - sc-414290-ACT from Santa Cruz Biotechnology
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LYPLAL1 CRISPR Activation Plasmid (h2) - sc-414290-ACT-2 from Santa Cruz Biotechnology
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LYPLAL1 Lentiviral Activation Particles (h) - sc-414290-LAC from Santa Cruz Biotechnology
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LYPLAL1 Lentiviral Activation Particles (h2) - sc-414290-LAC-2 from Santa Cruz Biotechnology
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LYPLAL1 siRNA (h) - sc-88625 from Santa Cruz Biotechnology
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LYPLAL1 shRNA Plasmid (h) - sc-88625-SH from Santa Cruz Biotechnology
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LYPLAL1 shRNA (h) Lentiviral Particles - sc-88625-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12863 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12863 from Sigma-Aldrich
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LYPLAL1 siRNA (Human) - CRJ4895 from Cohesion Biosciences
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shRNA set against Human LYPLAL1 (NM_138794.3) - SHH336123 from Creative biogene
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Human LYPLAL1 siRNA - orb275396 from Biorbyt
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LYPLAL1 shRNA Plasmid (Human) - CHJ4895 from Cohesion Biosciences
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LYPLAL1 miRNA 3'UTR clone - MiUTR3H-15435 from Creative biogene
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