Gene Symbol | CDSN |
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Entrez Gene | 1041 |
Alt Symbol | HTSS, HTSS1, HYPT2, PSS, PSS1, S |
Species | Human |
Gene Type | protein-coding |
Description | corneodesmosin |
Other Description | differentiated keratinocyte S protein |
Swissprots | Q7LA71 B0S7V2 Q9UBH8 Q9UIN6 O43509 Q7LA70 Q8IZU4 Q9NPE0 Q9NRH4 Q8N5P3 Q86Z04 Q9UIN9 Q8IZU6 Q9NRH6 Q5STD2 Q9UIN8 Q9NRH5 Q8IZU5 Q95IF9 Q9NRH8 Q9UIN7 Q9NPG5 Q9UIP0 Q9NRH7 B0UYZ7 Q15517 Q9NP52 Q5SQ85 |
Accessions | AAF78559 AAF78560 AAF78561 AAF78562 AAF78563 AAF78564 AAF78565 AAF78566 AAF78567 AAF78568 AAF78569 AAF78570 AAG02419 AAN70994 AAN70995 AAN70996 AAP94640 AAP94641 ACZ95707 AGG40963 BAC54948 BAF31283 CAB57266 CAB57267 CAB57268 CAB57269 CAB57270 CAB57271 CAB57272 EAX03358 Q15517 AF030130 AAC24196 AI768204 AK292636 BAF85325 AU134804 BC031993 AAH31993 DQ891583 ABM82509 DQ894777 ABM85703 L20815 AAA21321 NM_001264 NP_001255 |
Function | Important for the epidermal barrier integrity. {ECO:0000269|PubMed:20691404}. |
Subcellular Location | Secreted. Note=Found in corneodesmosomes, the intercellular structures that are involved in desquamation. |
Tissue Specificity | Exclusively expressed in skin. |
CDSN CRISPR/Cas9 KO Plasmid (h) - sc-406086 from Santa Cruz Biotechnology
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CDSN HDR Plasmid (h) - sc-406086-HDR from Santa Cruz Biotechnology
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CDSN Double Nickase Plasmid (h) - sc-406086-NIC from Santa Cruz Biotechnology
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CDSN Double Nickase Plasmid (h2) - sc-406086-NIC-2 from Santa Cruz Biotechnology
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CDSN CRISPR Activation Plasmid (h) - sc-406086-ACT from Santa Cruz Biotechnology
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CDSN CRISPR Activation Plasmid (h2) - sc-406086-ACT-2 from Santa Cruz Biotechnology
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CDSN Lentiviral Activation Particles (h) - sc-406086-LAC from Santa Cruz Biotechnology
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CDSN Lentiviral Activation Particles (h2) - sc-406086-LAC-2 from Santa Cruz Biotechnology
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CDSN siRNA (h) - sc-60347 from Santa Cruz Biotechnology
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CDSN shRNA Plasmid (h) - sc-60347-SH from Santa Cruz Biotechnology
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CDSN shRNA (h) Lentiviral Particles - sc-60347-V from Santa Cruz Biotechnology
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Corneodesmosin RNAi - H00001041-R01 from Novus Biologicals
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MISSION® esiRNA - EHU225551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5885 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5885 from Sigma-Aldrich
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CDSN siRNA (Human) - CRH0751 from Cohesion Biosciences
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CDSN - MBS8200722 from MyBioSource
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shRNA set against Human CDSN (NM_001264.4) - SHH261045 from Creative biogene
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Human CDSN siRNA - orb261253 from Biorbyt
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CDSN shRNA Plasmid (Human) - CHH0751 from Cohesion Biosciences
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CDSN miRNA 3'UTR clone - MiUTR3H-05112 from Creative biogene
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