Gene Symbol |
UBE2H
|
Entrez Gene |
7328
|
Alt Symbol |
E2-20K, GID3, UBC8, UBCH, UBCH2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ubiquitin-conjugating enzyme E2H
|
Other Description |
GID complex subunit 3, UBC8 homolog|ubiquitin carrier protein H|ubiquitin-conjugating enzyme E2 H|ubiquitin-conjugating enzyme E2-20K|ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)|ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8)|ubiquitin-protein ligase H
|
Swissprots |
Q7Z6F4 A4D1L6 P62256 C9JY93
|
Accessions |
AAS07548 EAL24098 EAL24099 EAW83733 EAW83734 EAW83735 EAW83736 EAW83737 P62256 AB451490 BAG70304 AK024519 AK026094 AK091088 AK316590 AL832212 AY302138 AAP57630 BC006277 AAH06277 BI088146 BT006756 AAP35402 CB995681 JF432609 ADZ15826 KJ534959 AHW56599 Z29328 CAA82525 Z29330 CAA82527 Z29331 CAA82528 XM_011516547 XP_011514849 NM_001202498 NP_001189427 NM_003344 NP_003335 NM_182697 NP_874356
|
Function |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A. {ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:8132613}.
|
Top Pathways |
Ubiquitin mediated proteolysis
|