| Gene Symbol |
STOM
|
| Entrez Gene |
2040
|
| Alt Symbol |
BND7, EPB7, EPB72
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
stomatin
|
| Other Description |
erythrocyte band 7 integral membrane protein|erythrocyte membrane protein band 7.2 (stomatin)|erythrocyte surface protein band 7.2|protein 7.2b
|
| Swissprots |
Q15609 Q14087 P27105 B1AM77 Q96FK4 Q5VX96
|
| Accessions |
AAC50296 CAA59436 CAY55995 CAY55996 EAW87493 EAW87494 P27105 AI224884 AK302977 BAG64120 AK304449 BAG65267 AK304518 BAG65322 AK307999 AL040491 AU137947 BC010703 AAH10703 BG701899 BI553227 BI763647 BM451470 BM925356 BP208523 CA447945 CR542100 CAG46897 DC368197 DQ891058 ABM81984 DQ894236 ABM85162 M81635 AAA58432 X60067 CAA42671 NM_001270526 NP_001257455 NM_001270527 NP_001257456 NM_004099 NP_004090 NM_198194 NP_937837 NR_073037
|
| Function |
Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
|
| Subcellular Location |
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cytoplasmic vesicle {ECO:0000250}. Note=Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts. Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles. Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
|
| Tissue Specificity |
Detected in erythrocytes (at protein level). Widely expressed. {ECO:0000269|PubMed:1547348, ECO:0000269|PubMed:23219802}.
|
