Gene Symbol | REN |
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Entrez Gene | 5972 |
Alt Symbol | HNFJ2 |
Species | Human |
Gene Type | protein-coding |
Description | renin |
Other Description | angiotensin-forming enzyme|angiotensinogenase|renin precursor, renal |
Swissprots | Q6FI38 P00797 Q6T5C2 |
Accessions | AAA60262 AAA60263 AAA60363 AAA60364 AAA60365 AAD03461 AAR03502 ABY87560 EAW91505 P00797 AF117822 AAD26254 BC033474 AAH33474 BC047752 AAH47752 BP321283 CR536498 CAG38737 HQ448652 ADQ33130 X00063 CAA24937 NM_000537 NP_000528 |
Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
Subcellular Location | Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2. |
Top Pathways | Renin-angiotensin system |
Renin CRISPR/Cas9 KO Plasmid (h) - sc-400890 from Santa Cruz Biotechnology
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Renin HDR Plasmid (h) - sc-400890-HDR from Santa Cruz Biotechnology
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Renin Double Nickase Plasmid (h) - sc-400890-NIC from Santa Cruz Biotechnology
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Renin Double Nickase Plasmid (h2) - sc-400890-NIC-2 from Santa Cruz Biotechnology
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Renin CRISPR Activation Plasmid (h) - sc-400890-ACT from Santa Cruz Biotechnology
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Renin CRISPR Activation Plasmid (h2) - sc-400890-ACT-2 from Santa Cruz Biotechnology
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Renin Lentiviral Activation Particles (h) - sc-400890-LAC from Santa Cruz Biotechnology
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Renin Lentiviral Activation Particles (h2) - sc-400890-LAC-2 from Santa Cruz Biotechnology
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Renin siRNA (h) - sc-41644 from Santa Cruz Biotechnology
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Renin shRNA Plasmid (h) - sc-41644-SH from Santa Cruz Biotechnology
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Renin shRNA (h) Lentiviral Particles - sc-41644-V from Santa Cruz Biotechnology
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Renin RNAi - H00005972-R01 from Novus Biologicals
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MISSION® esiRNA - EHU046491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1737 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1737 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01062 from Sigma-Aldrich
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REN siRNA (Human) - CRH4042 from Cohesion Biosciences
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REN - MBS8209188 from MyBioSource
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shRNA set against Human REN (NM_000537.3) - SHH391892 from Creative biogene
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Human REN siRNA - orb264544 from Biorbyt
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REN shRNA Plasmid (Human) - CHH4042 from Cohesion Biosciences
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REN miRNA 3'UTR clone - MiUTR3H-02011 from Creative biogene
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