Gene Symbol |
NUP155
|
Entrez Gene |
9631
|
Alt Symbol |
ATFB15, N155
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nucleoporin 155kDa
|
Other Description |
155 kDa nucleoporin|nuclear pore complex protein Nup155|nucleoporin 155kD
|
Swissprots |
O75694 Q9UBE9 Q9UFL5
|
Accessions |
AAD52966 EAW55957 EAW55958 EAW55959 O75694 AB018334 BAA34511 AI037962 AJ007558 CAA07553 AK002103 BAG51015 AK297143 BAG59644 AK315028 AL117585 CAB56007 BC039257 AAH39257 BM478072 BQ435836 BQ937467 BU601425 DA249538 DC401967 XM_011514164 XP_011512466 XM_011514165 XP_011512467 XM_011514166 XP_011512468 NM_001278312 NP_001265241 NM_004298 NP_004289 NM_153485 NP_705618
|
Function |
Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport. {ECO:0000250|UniProtKB:Q99P88}.
|
Subcellular Location |
Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P37199}. Nucleus membrane {ECO:0000250|UniProtKB:P37199}; Peripheral membrane protein {ECO:0000250|UniProtKB:P37199}; Cytoplasmic side {ECO:0000250|UniProtKB:P37199}. Nucleus membrane {ECO:0000250|UniProtKB:P37199}; Peripheral membrane protein {ECO:0000250|UniProtKB:P37199}; Nucleoplasmic side {ECO:0000250|UniProtKB:P37199}. Note=In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis. {ECO:0000250|UniProtKB:P37199}.
|
Tissue Specificity |
Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
|
Top Pathways |
RNA transport
|