Gene Symbol | LGSN |
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Entrez Gene | 51557 |
Alt Symbol | GLULD1, LGS |
Species | Human |
Gene Type | protein-coding |
Description | lengsin, lens protein with glutamine synthetase domain |
Other Description | glutamate-ammonia ligase (glutamine synthase) domain containing 1|glutamate-ammonia ligase domain-containing protein 1|lengsin |
Swissprots | Q0PVN9 A1L421 Q5TDP6 Q0PVP0 Q9NYJ0 |
Accessions | EAW88493 Q5TDP6 AF242388 AAF61255 BC130366 AAI30367 BC130368 AAI30369 DQ682605 ABG75902 DQ682606 ABG75903 XM_011535889 XP_011534191 XM_011535890 XP_011534192 XM_011535891 XP_011534193 XM_011535892 XP_011534194 XM_011535893 XP_011534195 NM_001143940 NP_001137412 NM_016571 NP_057655 |
Function | May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity (By similarity). {ECO:0000250}. |
Tissue Specificity | Abundantly expressed in lens. {ECO:0000269|PubMed:12107413, ECO:0000269|PubMed:17010935}. |
GLULD1 CRISPR/Cas9 KO Plasmid (h) - sc-409944 from Santa Cruz Biotechnology
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GLULD1 HDR Plasmid (h) - sc-409944-HDR from Santa Cruz Biotechnology
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GLULD1 Double Nickase Plasmid (h) - sc-409944-NIC from Santa Cruz Biotechnology
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GLULD1 Double Nickase Plasmid (h2) - sc-409944-NIC-2 from Santa Cruz Biotechnology
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GLULD1 CRISPR Activation Plasmid (h) - sc-409944-ACT from Santa Cruz Biotechnology
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GLULD1 CRISPR Activation Plasmid (h2) - sc-409944-ACT-2 from Santa Cruz Biotechnology
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GLULD1 Lentiviral Activation Particles (h) - sc-409944-LAC from Santa Cruz Biotechnology
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GLULD1 Lentiviral Activation Particles (h2) - sc-409944-LAC-2 from Santa Cruz Biotechnology
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GLULD1 siRNA (h) - sc-95576 from Santa Cruz Biotechnology
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GLULD1 shRNA Plasmid (h) - sc-95576-SH from Santa Cruz Biotechnology
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GLULD1 shRNA (h) Lentiviral Particles - sc-95576-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU149041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11683 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11683 from Sigma-Aldrich
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LGSN siRNA (Human) - CRH9830 from Cohesion Biosciences
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shRNA set against Human LGSN (NM_016571.2) - SHH329979 from Creative biogene
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Human LGSN siRNA - orb270332 from Biorbyt
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LGSN shRNA Plasmid (Human) - CHH9830 from Cohesion Biosciences
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LGSN miRNA 3'UTR clone - MiUTR4H-TG05047 from Creative biogene
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