| Gene Symbol |
GSTM3
|
| Entrez Gene |
2947
|
| Alt Symbol |
GST5, GSTB, GSTM3-3, GTM3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutathione S-transferase mu 3 (brain)
|
| Other Description |
GST class-mu 3|S-(hydroxyalkyl)glutathione lyase M3|brain GST|brain type mu-glutathione S-transferase|glutathione S-alkyltransferase M3|glutathione S-aralkyltransferase M3|glutathione S-aryltransferase M3|glutathione S-transferase M3 (brain)|glutathione S-transferase Mu 3|glutathione S-transferase, Mu-3|hGSTM3-3
|
| Swissprots |
Q96HA3 O60550 P21266
|
| Accessions |
AAC17866 ABV02583 EAW56409 P21266 AB209816 BAD93053 AI201498 AI570401 AK304300 BAG65154 AK313444 BAG36233 BC000088 AAH00088 BC008790 AAH08790 BC030253 BE392471 BG285419 BT019945 AAV38748 CR542108 CAG46905 DQ891834 ABM82760 EF363096 ABO72589 EU176637 ABW03438 J05459 AAA60964 XM_011541296 XP_011539598 NM_000849 NP_000840 NR_024537
|
| Function |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. {ECO:0000269|PubMed:10587441}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Testis and brain.
|
| Top Pathways |
Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|
