Gene Symbol |
TM9SF1
|
Entrez Gene |
10548
|
Alt Symbol |
HMP70, MP70
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
transmembrane 9 superfamily member 1
|
Other Description |
MP70 protein family member|multispanning membrane protein (70kD)|transmembrane protein 9 superfamily member 1
|
Swissprots |
Q86SZ6 D3DS65 O15321 Q96FI8
|
Accessions |
CAF02373 CCO75431 CCO75432 EAW66073 EAW66074 EAW66075 EAW66076 EAW66077 O15321 AA663295 AK292110 BAF84799 AK304642 BAG65421 AW015727 AW452952 BC010856 AAH10856 BM922952 BX161390 CAD61879 BX161494 CAD61941 DB524698 HY174389 U94831 AAC51782 NM_001014842 NP_001014842 NM_001289006 NP_001275935 NM_006405 NP_006396
|
Function |
Plays an essential role in autophagy. {ECO:0000269|PubMed:19029833}.
|
Subcellular Location |
Lysosome membrane {ECO:0000269|PubMed:19029833}; Multi-pass membrane protein {ECO:0000269|PubMed:19029833}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:19029833}; Multi-pass membrane protein {ECO:0000269|PubMed:19029833}.
|
Tissue Specificity |
Expressed in lung, pancreas, kidney, liver, placenta, skeletal muscle, heart and brain. The amount in skeletal muscle, heart and brain were considerably lower than in the other tissues. {ECO:0000269|PubMed:9332367}.
|