Gene Symbol | RCAN1 |
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Entrez Gene | 1827 |
Alt Symbol | ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of calcineurin 1 |
Other Description | Down syndrome candidate region 1|Down syndrome critical region gene 1|calcipressin-1|calcium and oxidant-inducible mRNA|modulatory calcineurin-interacting protein 1|myocyte-enriched calcineurin-interacting protein 1|near DSCR proline-rich protein |
Swissprots | Q9BU69 Q7Z555 Q6IBC6 O00582 D3DSF9 O00583 P53805 Q96R03 Q9UF15 Q9UME4 Q53XT0 |
Accessions | AAF21218 ABU54837 EAX09777 EAX09778 EAX09779 EAX09780 EAX09781 EAX09782 P53805 AF303449 AAG40774 AF400429 AAK92478 AI079710 AK055845 AK092184 BAG52494 AK131569 BAD18702 AK293293 BAH11486 AK299444 BAH13035 AL049369 AL556803 AY325903 AAP96743 BC002864 AAH02864 BT007363 AAP36027 BX419260 CR456878 CAG33159 CR542065 CAG46862 DA503835 DA586027 DB023862 DC331441 HQ448344 ADQ32824 U28833 AAB81557 U85265 AAB84370 U85266 AAB84371 U85267 AAB84372 XM_005260929 XP_005260986 XM_005260930 XP_005260987 NM_001285389 NP_001272318 NM_001285391 NP_001272320 NM_001285392 NP_001272321 NM_001285393 NP_001272322 NM_004414 NP_004405 NM_203417 NP_981962 NM_203418 NP_981963 |
Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. |
Tissue Specificity | Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues. |
Top Pathways | Oxytocin signaling pathway |
DSCR 1 CRISPR/Cas9 KO Plasmid (h) - sc-402694 from Santa Cruz Biotechnology
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DSCR 1 HDR Plasmid (h) - sc-402694-HDR from Santa Cruz Biotechnology
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DSCR 1 Double Nickase Plasmid (h) - sc-402694-NIC from Santa Cruz Biotechnology
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DSCR 1 Double Nickase Plasmid (h2) - sc-402694-NIC-2 from Santa Cruz Biotechnology
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DSCR 1 CRISPR Activation Plasmid (h) - sc-402694-ACT from Santa Cruz Biotechnology
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DSCR 1 CRISPR Activation Plasmid (h2) - sc-402694-ACT-2 from Santa Cruz Biotechnology
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DSCR 1 Lentiviral Activation Particles (h) - sc-402694-LAC from Santa Cruz Biotechnology
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DSCR 1 Lentiviral Activation Particles (h2) - sc-402694-LAC-2 from Santa Cruz Biotechnology
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DSCR 1 siRNA (h) - sc-45480 from Santa Cruz Biotechnology
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DSCR 1 shRNA Plasmid (h) - sc-45480-SH from Santa Cruz Biotechnology
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DSCR 1 shRNA (h) Lentiviral Particles - sc-45480-V from Santa Cruz Biotechnology
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RCN1 RNAi - H00005954-R01 from Novus Biologicals
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RCAN1 RNAi - H00001827-R03 from Novus Biologicals
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MISSION® esiRNA - EHU016781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18089 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18089 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10241 from Sigma-Aldrich
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RCAN1 siRNA (Human) - CRH1276 from Cohesion Biosciences
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RCAN1 RNAi - H00001827-R02 from Novus Biologicals
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RCAN1 RNAi - H00001827-R01 from Novus Biologicals
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RCAN1 - MBS8221710 from MyBioSource
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shRNA set against Human DSCR1(NM_203418.1) - SHH016283 from Creative biogene
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shRNA set against Human DSCR1(NM_004414.5) - SHH016319 from Creative biogene
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shRNA set against Human DSCR1(NM_203417.1) - SHH016337 from Creative biogene
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RCAN1 shRNA Plasmid (Human) - CHH1276 from Cohesion Biosciences
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