| Gene Symbol |
KIR2DL2
|
| Entrez Gene |
3803
|
| Alt Symbol |
CD158B1, CD158b, NKAT-6, NKAT6, p58.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
|
| Other Description |
CD158 antigen-like family member B1|MHC class I NK cell receptor|killer cell immunoglobulin-like receptor 2DL2|natural killer-associated transcript 6|p58 NK receptor CL-43|p58 natural killer cell receptor clone CL-43
|
| Swissprots |
C6EVR8 P43627 Q14951
|
| Accessions |
ACI49715 ACI49716 ACI49717 ACX71617 ACX71620 ADJ94533 ADJ94635 ADJ94646 ADJ94677 CAX15032 P43627 AF285434 AAG34925 AY366242 AAR16200 BC152936 AAI52937 KP260924 AKE48533 L76669 AAB36597 U24075 AAC50334 XM_011547159 XP_011545461 XM_011547550 XP_011545852 NM_014219 NP_055034
|
| Function |
Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. {ECO:0000269|PubMed:10097129}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Natural killer cell mediated cytotoxicity, Graft-versus-host disease, Antigen processing and presentation
|