| Gene Symbol |
COL21A1
|
| Entrez Gene |
81578
|
| Alt Symbol |
COLA1L, FP633, dJ682J15.1, dJ708F5.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collagen, type XXI, alpha 1
|
| Other Description |
alpha 1 chain-like collagen|alpha 1 type XXI collagen|collagen alpha-1(XXI) chain
|
| Swissprots |
Q8WXV8 Q96P44 Q9H0V3 A6NIX5 Q49A51 Q71RF4 B2R8J9
|
| Accessions |
AAL86699 ACJ66843 EAX04448 EAX04449 EAX04450 EAX04451 EAX04452 Q96P44 AF330693 AAL50033 AF370383 AAQ15219 AF414088 AAL02227 AK096444 BAG53292 AK126586 AK313398 BAG36196 AL136624 CAB66559 BC045597 AAH45597 BC126108 AAI26109 BC143862 BC143863 BC143864 BC143865 AAI43866 BP231679 XM_006715223 XP_006715286 XM_006715225 XP_006715288 XM_011514923 XP_011513225 XM_011514924 XP_011513226 XM_011514925 XP_011513227 XM_011514926 XP_011513228 XM_011514927 XP_011513229 XR_241922 XR_926314 NM_030820 NP_110447
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:11863369}. Cytoplasm {ECO:0000269|PubMed:11863369}. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
|
| Tissue Specificity |
Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes. Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium. {ECO:0000269|PubMed:11566190, ECO:0000269|PubMed:11863369}.
|
| Top Pathways |
Protein digestion and absorption, Proteoglycans in cancer
|
