Gene Symbol | C1QC |
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Entrez Gene | 714 |
Alt Symbol | C1Q-C, C1QG |
Species | Human |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent, C chain |
Other Description | complement C1q subcomponent subunit C|complement component 1, q subcomponent, gamma polypeptide |
Swissprots | Q96H05 Q7Z502 P02747 Q96DL2 |
Accessions | EAW95016 EAW95017 EAW95018 P02747 AF087892 AAP97191 AK057792 BAB71575 AK130613 AK226152 AM392881 CAL37759 AM393232 CAL38110 AM393519 CAL38396 BC009016 AAH09016 BG060138 CB995661 DA849505 NM_001114101 NP_001107573 NM_172369 NP_758957 |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection |
C1QG-Over-expression-Lysate - LY12340a from Abgent, a WuXi AppTec company
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C1QC 293T Cell Transient Overexpression Lysate(Denatured) - H00000714-T01 from Acris Antibodies
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C1QC 293 Cell Lysate - 403062 from ABBIOTEC
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Complement Component C1qC Overexpression Lysate (Native) - NBL1-08339 from Novus Biologicals
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Complement Component C1qC Overexpression Lysate (Native) - NBP2-09393 from Novus Biologicals
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C1q-C (h): 293 Lysate - sc-110932 from Santa Cruz Biotechnology
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C1q-C (h2): 293 Lysate - sc-128184 from Santa Cruz Biotechnology
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C1QC Over-expression Lysate Product - GWB-2D6C00 from Genway Biotech
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Complement Component C1qC Overexpression Lysate (Denatured) - H00000714-T02 from Novus Biologicals
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Complement Component C1qC Overexpression Lysate (Denatured) - H00000714-T01 from Novus Biologicals
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Panoply™ Human C1QC Knockdown Stable Cell Line - CSC-DC001919 from Creative biogene
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