Gene Symbol | SUCLG2 |
---|---|
Entrez Gene | 8801 |
Alt Symbol | GBETA |
Species | Human |
Gene Type | protein-coding |
Description | succinate-CoA ligase, GDP-forming, beta subunit |
Other Description | GTP-specific succinyl-CoA synthetase beta subunit|GTP-specific succinyl-CoA synthetase subunit beta|SCS-betaG|succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial|succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial|succinyl-CoA synthetase beta-G chain|succinyl-CoA synthetase, beta-G chain |
Swissprots | C9JVT2 Q6NUH7 Q8WUQ1 O95195 Q86VX8 Q96I99 |
Accessions | EAW65456 EAW65457 Q96I99 AF058954 AAC64397 AF131748 AAD20032 AK294598 BAH11821 AK310527 AL050226 CAB43323 BC007716 AAH07716 BC019868 AAH19868 BC035149 AAH35149 BC047024 AAH47024 BC068602 AAH68602 R41924 XR_245062 XR_940506 NM_001177599 NP_001171070 NM_003848 NP_003839 |
Function | Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA. {ECO:0000250}. |
Subcellular Location | Mitochondrion. |
Tissue Specificity | Mainly expressed in liver, kidney, heart, spleen and skeletal muscle. Also found in intestine and colon, and in low amounts in lung, brain, prostate, testis and ovary. {ECO:0000269|PubMed:9765291}. |
Top Pathways | Citrate cycle (TCA cycle), Carbon metabolism, Propanoate metabolism |
SUCLG2 CRISPR/Cas9 KO Plasmid (h) - sc-416240 from Santa Cruz Biotechnology
|
||||||||
SUCLG2 HDR Plasmid (h) - sc-416240-HDR from Santa Cruz Biotechnology
|
||||||||
SUCLG2 Double Nickase Plasmid (h) - sc-416240-NIC from Santa Cruz Biotechnology
|
||||||||
SUCLG2 Double Nickase Plasmid (h2) - sc-416240-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SUCLG2 CRISPR Activation Plasmid (h) - sc-416240-ACT from Santa Cruz Biotechnology
|
||||||||
SUCLG2 CRISPR Activation Plasmid (h2) - sc-416240-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SUCLG2 Lentiviral Activation Particles (h) - sc-416240-LAC from Santa Cruz Biotechnology
|
||||||||
SUCLG2 Lentiviral Activation Particles (h2) - sc-416240-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SUCLG2 siRNA (h) - sc-77883 from Santa Cruz Biotechnology
|
||||||||
SUCLG2 shRNA Plasmid (h) - sc-77883-SH from Santa Cruz Biotechnology
|
||||||||
SUCLG2 shRNA (h) Lentiviral Particles - sc-77883-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU140901 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20804 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20804 from Sigma-Aldrich
|
||||||||
SUCLG2 siRNA (Human) - CRH5801 from Cohesion Biosciences
|
||||||||
SUCLG2 - MBS8240674 from MyBioSource
|
||||||||
shRNA set against Human SUCLG2 (NM_003848.3) - SHH420588 from Creative biogene
|
||||||||
SUCLG2 shRNA Plasmid (Human) - CHH5801 from Cohesion Biosciences
|
||||||||
SUCLG2 miRNA 3'UTR clone - MiUTR3H-06385 from Creative biogene
|