Gene Symbol | CFD |
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Entrez Gene | 1675 |
Alt Symbol | ADIPSIN, ADN, DF, PFD |
Species | Human |
Gene Type | protein-coding |
Description | complement factor D (adipsin) |
Other Description | C3 convertase activator|D component of complement (adipsin)|complement factor D|complement factor D preproprotein|properdin factor D |
Swissprots | Q86VJ5 Q8WZB4 Q8N4E0 Q5U5S1 P00746 B4DV76 |
Accessions | EAW69588 P00746 AJ313463 CAC48304 AK300963 BAG62588 BC034529 AAH34529 BC040146 AAH40146 BC051001 AAH51001 BC057807 AAH57807 BG573629 BI763909 CR536575 CAG38812 DQ884409 ABI63376 M84526 AAA35527 NM_001928 NP_001919 |
Function | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Staphylococcus aureus infection |
Human Factor D full length protein - ab139231 from Abcam
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Human Factor D full length protein - ab168867 from Abcam
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Human Factor D full length protein - ab202242 from Abcam
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CFD / Factor D / Adipsin Antibody Blocking Peptide - LS-E1418 from LifeSpan Bioscience
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CFD / Factor D / Adipsin Antibody Blocking Peptide - LS-E22034 from LifeSpan Bioscience
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Complement Factor D/Adipsin Recombinant Protein - H00001675-P01 from Novus Biologicals
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Recombinant Human Complement Factor D/Adipsin Protein - NBP2-22797 from Novus Biologicals
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CFD-Antibody-N-term-Blocking-peptide - BP12089a from Abgent, a WuXi AppTec company
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Recombinant Human Complement Factor D, CF - 1824-SE-010 from R&D Systems
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Human CFD His tag protein - orb84507 from Biorbyt
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Human Adipsin protein - orb191054 from Biorbyt
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Adipsin protein - orb197639 from Biorbyt
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Adipsin Blocking Peptide - 33R-11010 from Fitzgerald
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CFD Blocking Peptide - 33R-3540 from Fitzgerald
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CFD protein - 80R-4236 from Fitzgerald
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CFD protein (His tag) - 30R-2941 from Fitzgerald
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Adipsin Blocking Peptide - abx161009 from Abbexa
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Human Complement Factor D Protein - abx066074 from Abbexa
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Complement factor D (26-253, His-tag) - AR50701PU-N from Acris Antibodies
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Complement factor D (26-253, His-tag) - AR50701PU-S from Acris Antibodies
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Complement factor D (21-253, His-tag) - AR51918PU-N from Acris Antibodies
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Complement factor D (21-253, His-tag) - AR51918PU-S from Acris Antibodies
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Complement factor D - H00001675-P01 from Acris Antibodies
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Complement factor D - H00001675-P01-10 from Acris Antibodies
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Complement factor D - H00001675-P01-25 from Acris Antibodies
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