Gene Symbol | EPB41L1 |
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Entrez Gene | 2036 |
Alt Symbol | 4.1N, MRD11 |
Species | Human |
Gene Type | protein-coding |
Description | erythrocyte membrane protein band 4.1-like 1 |
Other Description | band 4.1-like protein 1|neuron-type nonerythroid protein 4.1|neuronal protein 4.1 |
Swissprots | Q96L65 Q4VXM8 Q4VXM6 Q9H4G0 Q4VXM7 Q4VXN4 Q6ZT61 Q96CV5 O15046 Q8IUU7 |
Accessions | EAW76144 EAW76145 EAW76146 Q9H4G0 AB002336 BAA20796 AK096848 BAG53378 AK126875 BAC86733 AK299817 BAH13139 AY049789 AAL15446 BC013885 AAH13885 BC040259 AAH40259 BC113858 AAI13859 BC113899 AAI13900 BC131796 AAI31797 BI457725 BX537978 CAD97941 CR936825 DB503878 DQ891352 ABM82278 DQ894531 ABM85457 EU831995 ACE87436 EU832088 ACE86750 EU832836 ACE87847 GQ129232 ACT64366 HG511342 XM_011528664 XP_011526966 XM_011528665 XP_011526967 XM_011528666 XP_011526968 XM_011528667 XP_011526969 XM_011528668 XP_011526970 XM_011528669 XP_011526971 XM_011528670 XP_011526972 XM_011528671 XP_011526973 XM_011528672 XP_011526974 XM_011528673 XP_011526975 XM_011528674 XP_011526976 XM_011528675 XP_011526977 XM_011528676 XP_011526978 XM_011528677 XP_011526979 XM_011528678 XP_011526980 XM_011528679 XP_011526981 XM_011528680 XP_011526982 XM_011528681 XP_011526983 XM_011528682 XP_011526984 XM_011528683 XP_011526985 XM_011528684 XP_011526986 XM_011528685 XP_011526987 XM_011528686 XP_011526988 NM_001258329 NP_001245258 NM_001258330 NP_001245259 NM_001258331 NP_001245260 NM_012156 NP_036288 NM_177996 NP_818932 |
Function | May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle. |
Top Pathways | Tight junction |
4.1N CRISPR/Cas9 KO Plasmid (h) - sc-404584 from Santa Cruz Biotechnology
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4.1N HDR Plasmid (h) - sc-404584-HDR from Santa Cruz Biotechnology
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4.1N Double Nickase Plasmid (h) - sc-404584-NIC from Santa Cruz Biotechnology
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4.1N Double Nickase Plasmid (h2) - sc-404584-NIC-2 from Santa Cruz Biotechnology
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4.1N CRISPR Activation Plasmid (h) - sc-404584-ACT from Santa Cruz Biotechnology
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4.1N CRISPR Activation Plasmid (h2) - sc-404584-ACT-2 from Santa Cruz Biotechnology
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4.1N Lentiviral Activation Particles (h) - sc-404584-LAC from Santa Cruz Biotechnology
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4.1N Lentiviral Activation Particles (h2) - sc-404584-LAC-2 from Santa Cruz Biotechnology
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4.1N siRNA (h) - sc-105013 from Santa Cruz Biotechnology
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4.1N shRNA Plasmid (h) - sc-105013-SH from Santa Cruz Biotechnology
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4.1N shRNA (h) Lentiviral Particles - sc-105013-V from Santa Cruz Biotechnology
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EPB41L1 RNAi - H00002036-R02 from Novus Biologicals
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EPB41L1 RNAi - H00002036-R01 from Novus Biologicals
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MISSION® esiRNA - EHU063821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7901 from Sigma-Aldrich
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EPB41L1 siRNA (Human) - CRH1413 from Cohesion Biosciences
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EPB41L1 - MBS8240144 from MyBioSource
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shRNA set against Human EPB41L1 (NM_012156.2) - SHH286213 from Creative biogene
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EPB41L1 shRNA Plasmid (Human) - CHH1413 from Cohesion Biosciences
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EPB41L1 miRNA 3'UTR clone - MiUTR1H-03247 from Creative biogene
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