| Gene Symbol |
CYP3A5
|
| Entrez Gene |
1577
|
| Alt Symbol |
CP35, CYPIIIA5, P450PCN3, PCN3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 3, subfamily A, polypeptide 5
|
| Other Description |
aryl hydrocarbon hydroxylase|cytochrome P450 3A5|cytochrome P450 HLp2|cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5|cytochrome P450-PCN3|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
|
| Swissprots |
Q53WY8 Q75MV0 A4D289 Q9HB56 B7Z5I7 P20815
|
| Accessions |
AAB00083 AAG32288 AAK73691 AAS02016 ABG25922 CCQ42992 EAL23868 EAW76638 EAW76639 EAW76640 EAW76641 EAW76642 P20815 AA076026 AF355801 AAK73689 AF355802 AAK73690 AF355804 AJ563378 CAD91347 AJ563379 CAD91649 AK055879 AK223008 BAD96728 AK296205 BAH12282 AK299002 BAH12923 AK309166 AK313813 BAG36549 BC022298 BC025176 BC026255 BC033862 AAH33862 BX537676 CAD97807 BX648856 DC383127 DQ890743 ABM81669 DQ893913 ABM84839 DQ896802 ABM87801 EU176488 ABW03289 J04813 AAA02993 L26985 X90579 XM_006715859 XP_006715922 XM_011515843 XP_011514145 XM_011515844 XP_011514146 XM_011515845 XP_011514147 XM_011515846 XP_011514148 XM_011515847 XP_011514149 XR_927383 NM_000777 NP_000768 NM_001190484 NP_001177413 NM_001291829 NP_001278758 NM_001291830 NP_001278759 NR_033807 NR_033810 NR_033811 NR_033812
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|