| Gene Symbol | UTY |
|---|---|
| Entrez Gene | 7404 |
| Alt Symbol | KDM6AL, UTY1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| Other Description | histone demethylase UTY|ubiquitous TPR motif protein UTY|ubiquitously transcribed TPR gene on Y chromosome|ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome|ubiquitously transcribed tetratricopeptide repeat gene, Y-linked|ubiquitously-transcribed TPR protein on the Y chromosome|ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein |
| Swissprots | F5H4V7 O14607 A8K9Z3 E1U1A0 F8W8R7 E1U199 O14608 |
| Accessions | AAF36521 AAF77052 AAT86083 ACP43292 ACP43293 ACP43294 EAW91613 O14607 AF000994 AAC51841 AF000995 AAC51842 AF000996 AAC51843 AK292858 BAF85547 AK308952 AY682463 AAU87837 AY730613 AAU93524 AY769061 AAX07231 AY769062 AAX07232 AY769063 AAX07233 AY769064 AAX07234 AY769065 AAX07235 AY769066 AAX07236 AY769067 AAX07237 AY769068 AAX07238 AY769069 AAX07239 AY934848 AAY16579 AY934849 AAY16580 AY934850 AAY16581 AY934851 AAY16582 AY934852 AAY16583 AY934853 AAY16584 AY934854 AAY16585 AY934855 AAY16586 AY934856 AAY16587 AY934857 AAY16588 BC012581 BC029389 BC051718 AAH51718 BC071744 AAH71744 BC140391 AAI40392 CR936684 DQ012094 AAY68207 DQ140388 ABA25869 DQ140389 ABA25870 DQ140390 ABA25871 DQ341385 ABC87284 DQ341386 ABC87285 DQ341387 ABC87286 DQ345542 ABC75707 DQ345543 ABC75708 DQ345544 ABC75709 DQ350456 ABC73373 DQ350457 ABC73374 DQ350458 ABC73375 DQ350459 ABC73376 EF491796 EF612660 ABR09226 EF612661 ABR09227 EF612662 ABR09228 EF612663 ABR09229 EF612664 ABR09230 EF612665 ABR09231 EF612666 ABR09232 EF612667 ABR09233 EF612668 ABR09234 EF612669 ABR09235 EF612670 ABR09236 EF612671 ABR09237 EF612672 ABR09238 EF612673 ABR09239 EF612674 ABR09240 EF612675 ABR09241 EF612676 ABR09242 EF612677 ABR09243 EF612678 ABR09244 EF612679 ABR09245 EF612680 ABR09246 EF612681 ABR09247 EF612682 ABR09248 EF612683 ABR09249 EF612684 ABR09250 EF612685 ABR09251 EF612686 ABR09252 EF612687 ABR09253 EF612688 ABR09254 EF612689 ABR09255 EF612690 ABR09256 EF612691 ABR09257 EF612692 ABR09258 EF612693 ABR09259 EF612694 ABR09260 EF612695 ABR09261 EF612696 ABR09262 EF612697 ABR09263 EF612698 ABR09264 EF612699 ABR09265 EF653165 ABV49411 EF653166 ABV49412 EF653167 ABV49413 EF653168 ABV49414 EF653169 ABV49415 EF653170 ABV49416 EF653171 ABV49417 EF653172 ABV49418 EF653173 ABV49419 EF653174 ABV49420 EF653175 ABV49421 EF653176 ABV49422 EF653177 ABV49423 EF653178 ABV49424 EF653179 ABV49425 EF653180 ABV49426 EF653181 ABV49427 EF653182 ABV49428 EF653183 ABV49429 EF653184 ABV49430 EF653185 ABV49431 EF653186 ABV49432 EF653187 ABV49433 EF653188 ABV49434 EF653189 ABV49435 EF653190 ABV49436 EF653191 ABV49437 EF653192 ABV49438 EF653193 ABV49439 EF653194 ABV49440 EF653195 ABV49441 EF653196 ABV49442 EF653197 ABV49443 EF653198 ABV49444 EF653199 ABV49445 EF653200 ABV49446 EF653201 ABV49447 EF653202 ABV49448 EF653203 ABV49449 EF653204 ABV49450 EF653205 ABV49451 EF653206 ABV49452 EF653207 ABV49453 EF653208 ABV49454 EF653209 ABV49455 EF653210 ABV49456 EF653211 ABV49457 EF653212 ABV49458 EF653213 ABV49459 EF653214 ABV49460 EF653215 ABV49461 EF653216 ABV49462 EF653217 ABV49463 EF653218 ABV49464 EF653219 ABV49465 EF653220 ABV49466 EF653221 ABV49467 EF653222 ABV49468 EF653223 ABV49469 EF653224 ABV49470 EF685283 ABS19004 EF685284 ABS19005 EF685285 ABS19006 EF685286 ABS19007 EF685287 ABS19008 EF685288 ABS19009 EF685289 ABS19010 EF685290 ABS19011 EF685291 ABS19012 EF685292 ABS19013 EF685293 ABS19014 EF685294 ABS19015 EF685295 ABS19016 EF685296 ABS19017 EF685297 ABS19018 EF685298 ABS19019 EF685299 ABS19020 EF685300 ABS19021 EF685301 ABS19022 EF685302 ABS19023 EF685303 ABS19024 EF685304 ABS19025 EF685305 ABS19026 EF685306 ABS19027 EF685307 ABS19028 EF685308 ABS19029 EF685309 ABS19030 EF685310 ABS19031 EF685311 ABS19032 EF685312 ABS19033 EF685313 ABS19034 EF685314 ABS19035 EF685315 ABS19036 EF685316 ABS19037 EF685317 ABS19038 EF685318 ABS19039 EF685319 ABS19040 EF685320 ABS19041 EF685321 ABS19042 EF685322 ABS19043 EF685323 ABS19044 EF685324 ABS19045 EF685325 ABS19046 EF685326 ABS19047 EF685327 ABS19048 EF685328 ABS19049 EF685329 ABS19050 EF685330 ABS19051 EF685331 ABS19052 EF685332 ABS19053 EF685333 ABS19054 EF685334 ABS19055 EF685335 ABS19056 EF685336 ABS19057 EF685337 ABS19058 EF685338 ABS19059 EF685339 ABS19060 EF685340 ABS19061 EF685341 ABS19062 EF685342 ABS19063 EU026275 ABV82606 EU026276 ABV82607 EU026277 ABV82608 EU026278 ABV82609 EU026279 ABV82610 EU026280 ABV82611 EU026281 ABV82612 EU026282 ABV82613 EU026284 ABV82615 EU026285 ABV82616 EU026286 ABV82617 EU026287 ABV82618 EU026288 ABV82619 EU026289 ABV82620 EU026290 ABV82621 EU026292 ABV82623 EU026293 ABV82624 EU026294 ABV82625 EU026295 ABV82626 EU026296 ABV82627 EU026297 ABV82628 EU026298 ABV82629 EU026299 ABV82630 EU026300 ABV82631 EU026301 ABV82632 EU026302 ABV82633 EU026303 ABV82634 EU026304 ABV82635 EU026305 ABV82636 EU026306 ABV82637 EU026307 ABV82638 EU026308 ABV82639 EU026309 ABV82640 EU026310 ABV82641 EU026311 ABV82642 EU026312 ABV82643 EU026313 ABV82644 EU026314 ABV82645 EU026315 ABV82646 EU026316 ABV82647 EU026317 ABV82648 EU026318 ABV82649 EU026319 ABV82650 EU026320 ABV82651 EU026321 ABV82652 EU026322 ABV82653 EU026323 ABV82654 EU026324 ABV82655 EU026325 ABV82656 EU026326 ABV82657 EU026327 ABV82658 EU026328 ABV82659 EU026329 ABV82660 EU026330 ABV82661 EU026331 ABV82662 EU026332 ABV82663 EU026333 ABV82664 EU026334 ABV82665 EU026335 ABV82666 EU026336 ABV82667 EU026337 ABV82668 EU026338 ABV82669 EU026339 ABV82670 EU026340 ABV82671 EU026341 ABV82672 EU026342 ABV82673 EU026343 ABV82674 EU026344 ABV82675 EU026345 ABV82676 EU026346 ABV82677 EU026347 ABV82678 EU026348 ABV82679 EU026349 ABV82680 EU026350 ABV82681 EU026351 ABV82682 EU116343 ABV82683 EU116344 ABV82684 EU116345 ABV82685 EU116346 ABV82686 EU116347 ABV82687 EU116348 ABV82688 EU116349 ABV82689 EU116350 ABV82690 EU116351 ABV82691 EU116352 ABV82692 EU116353 ABV82693 EU163941 ABW16939 EU163942 ABW16940 EU163943 ABW16941 XM_005262518 XP_005262575 XM_006724875 XP_006724938 XM_006724876 XP_006724939 XM_011531441 XP_011529743 XM_011531442 XP_011529744 XM_011531443 XP_011529745 XM_011531444 XP_011529746 XM_011531445 XP_011529747 XM_011531446 XP_011529748 XM_011531447 XP_011529749 XM_011531448 XP_011529750 XM_011531449 XP_011529751 XM_011531450 XP_011529752 XM_011531451 XP_011529753 XM_011531452 XP_011529754 XM_011531453 XP_011529755 XM_011531454 XP_011529756 XM_011531455 XP_011529757 XM_011531456 XP_011529758 XM_011531457 XP_011529759 XM_011531458 XP_011529760 XM_011531459 XP_011529761 XM_011531460 XP_011529762 XM_011531461 XP_011529763 XM_011531462 XP_011529764 XM_011531463 XP_011529765 XM_011531464 XP_011529766 XM_011531465 XP_011529767 XM_011531466 XP_011529768 XM_011531467 XP_011529769 XR_938608 NM_001258249 NP_001245178 NM_001258250 NP_001245179 NM_001258251 NP_001245180 NM_001258252 NP_001245181 NM_001258253 NP_001245182 NM_001258254 NP_001245183 NM_001258255 NP_001245184 NM_001258256 NP_001245185 NM_001258257 NP_001245186 NM_001258258 NP_001245187 NM_001258259 NP_001245188 NM_001258260 NP_001245189 NM_001258261 NP_001245190 NM_001258262 NP_001245191 NM_001258263 NP_001245192 NM_001258264 NP_001245193 NM_001258265 NP_001245194 NM_001258266 NP_001245195 NM_001258267 NP_001245196 NM_001258268 NP_001245197 NM_001258269 NP_001245198 NM_001258270 NP_001245199 NM_007125 NP_009056 NM_182659 NP_872600 NM_182660 NP_872601 NR_047596 NR_047597 NR_047598 NR_047599 NR_047600 NR_047601 NR_047602 NR_047603 NR_047604 NR_047605 NR_047606 NR_047607 NR_047608 NR_047609 NR_047610 NR_047611 NR_047612 NR_047613 NR_047614 NR_047615 NR_047616 NR_047617 NR_047618 NR_047619 NR_047620 NR_047621 NR_047622 NR_047623 NR_047624 NR_047625 NR_047626 NR_047627 NR_047628 NR_047629 NR_047630 NR_047631 NR_047632 NR_047633 NR_047634 NR_047635 NR_047636 NR_047637 NR_047638 NR_047639 NR_047640 NR_047641 NR_047642 NR_047643 NR_047644 NR_047645 NR_047646 NR_047647 |
| Function | Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity. {ECO:0000269|PubMed:24798337}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Top Pathways | Transcriptional misregulation in cancer |
UTY CRISPR/Cas9 KO Plasmid (h) - sc-416327 from Santa Cruz Biotechnology
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UTY HDR Plasmid (h) - sc-416327-HDR from Santa Cruz Biotechnology
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UTY Double Nickase Plasmid (h) - sc-416327-NIC from Santa Cruz Biotechnology
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UTY Double Nickase Plasmid (h2) - sc-416327-NIC-2 from Santa Cruz Biotechnology
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UTY CRISPR Activation Plasmid (h) - sc-416327-ACT from Santa Cruz Biotechnology
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UTY CRISPR Activation Plasmid (h2) - sc-416327-ACT-2 from Santa Cruz Biotechnology
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UTY Lentiviral Activation Particles (h) - sc-416327-LAC from Santa Cruz Biotechnology
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UTY Lentiviral Activation Particles (h2) - sc-416327-LAC-2 from Santa Cruz Biotechnology
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UTY siRNA (h) - sc-91538 from Santa Cruz Biotechnology
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UTY shRNA Plasmid (h) - sc-91538-SH from Santa Cruz Biotechnology
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UTY shRNA (h) Lentiviral Particles - sc-91538-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU115561 from Sigma-Aldrich
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MISSION® esiRNA - EHU073051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22625 from Sigma-Aldrich
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UTY siRNA (Human) - CRH5064 from Cohesion Biosciences
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UTY - MBS8216996 from MyBioSource
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shRNA set against Human UTY(NM_182660.1) - SHL119718 from Creative biogene
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shRNA set against Human UTY(NM_182659.1) - SHL119754 from Creative biogene
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UTY shRNA Plasmid (Human) - CHH5064 from Cohesion Biosciences
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UTY miRNA 3'UTR clone - MiUTR1H-11085 from Creative biogene
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UTY miRNA 3'UTR clone - MiUTR3H-03045 from Creative biogene
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UTY miRNA 3'UTR clone - MiUTR3H-03047 from Creative biogene
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