ATP11C

Gene Symbol	ATP11C
Entrez Gene	286410
Alt Symbol	ATPIG, ATPIQ
Species	Human
Gene Type	protein-coding
Description	ATPase, class VI, type 11C
Other Description	P4-ATPase flippase complex alpha subunit ATP11C|phospholipid-transporting ATPase IG|probable phospholipid-transporting ATPase IG
Swissprots	Q5JT72 Q5JT71 Q70IJ9 Q8NB49 Q5JT69 Q6ZND5 Q5JT70 Q6ZU50 Q70IK0 Q8WX24 Q5JT73 Q6ZUP7
Accessions	EAW88424 EAW88425 Q8NB49 AA829385 AJ580093 CAE30472 AJ580094 CAE30473 AK091552 BAC03692 AK093835 AK125474 BAC86172 AK125476 AK125986 BAC86377 AK131262 BAD18440 BC132728 BC132730 BC172372 AAI72372 BX648320 BX648981 D16467 DB348089 XM_011531320 XP_011529622 XM_011531321 XP_011529623 XM_011531322 XP_011529624 XM_011531323 XP_011529625 XM_011531324 XP_011529626 XM_011531325 XP_011529627 XM_011531326 XP_011529628 XM_011531327 XP_011529629 NM_001010986 NP_001010986 NM_173694 NP_775965
Function	Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Required for B cell differentiation past the pro-B cell stage. Seems to mediate phosphatidylserine (PS) flipping in pro-B cells. May be involved in the transport of cholestatic bile acids (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21914794}; Multi-pass membrane protein {ECO:0000269|PubMed:21914794}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21914794}. Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A. Some cell membrane localization observed in the presence of TMEM30B.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:15533723}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATP11C protein fragment - ab166228 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ATP11C Antibody Blocking Peptide - LS-E7841 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATP11C Antibody Blocking Peptide - LS-E16391 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ATP11C Protein - H00286410-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATP11C-Antibody-Center-Blocking-peptide - BP5446c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Atp11c Blocking Peptide - 33R-3401 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ATP11C - H00286410-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP11C - H00286410-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP11C fusion protein - ag20153 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ATP11C Recombinant Protein Antigen - NBP1-88902PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ATP11C Peptide, Human - M34GP01126H from Creative Peptides Category Peptide Source Synthetic. Species Human

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