| Gene Symbol |
RAD50
|
| Entrez Gene |
855471
|
| Alt Symbol |
-
|
| Species |
Yeast
|
| Gene Type |
protein-coding
|
| Description |
MRX complex DNA-binding subunit
|
| Other Description |
-
|
| Swissprots |
D6W0U3 P12753
|
| Accessions |
DAA10309 P12753 NM_001183088 NP_014149
|
| Function |
Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific exonuclease activity. Rad50 provides ATP-dependent control of mre11 by unwinding and/or repositioning DNA ends into the mre11 active site.
|
| Top Pathways |
Homologous recombination, Non-homologous end-joining
|