Gene Symbol | RCL1 |
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Entrez Gene | 10171 |
Alt Symbol | RNAC, RPCL1 |
Species | Human |
Gene Type | protein-coding |
Description | RNA terminal phosphate cyclase-like 1 |
Other Description | RNA 3'-terminal phosphate cyclase-like protein|RNA cyclase homolog |
Swissprots | Q5VZU1 Q9H9D0 D3DRI2 Q9Y2P8 Q5VYW9 Q9P044 Q9NY00 |
Accessions | EAW58776 EAW58777 Q9Y2P8 AF067172 AAD32456 AF161456 AAF29016 AI688431 AJ276894 CAB89811 AK022904 BAB14300 AK225872 AL518076 AL560629 BC001025 AAH01025 BI859171 CA422524 DB024289 DB448951 EF553527 ABQ66271 EU831474 ACE87161 EU831561 ACE86480 JF432531 ADZ15748 XM_006716715 XP_006716778 XM_011517673 XP_011515975 NM_001286699 NP_001273628 NM_001286700 NP_001273629 NM_001286701 NP_001273630 NM_005772 NP_005763 |
Function | Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000250}. |
Top Pathways | Ribosome biogenesis in eukaryotes |
RCL1 CRISPR/Cas9 KO Plasmid (h) - sc-411426 from Santa Cruz Biotechnology
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RCL1 HDR Plasmid (h) - sc-411426-HDR from Santa Cruz Biotechnology
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RCL1 Double Nickase Plasmid (h) - sc-411426-NIC from Santa Cruz Biotechnology
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RCL1 Double Nickase Plasmid (h2) - sc-411426-NIC-2 from Santa Cruz Biotechnology
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RCL1 CRISPR Activation Plasmid (h) - sc-411426-ACT from Santa Cruz Biotechnology
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RCL1 CRISPR Activation Plasmid (h2) - sc-411426-ACT-2 from Santa Cruz Biotechnology
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RCL1 Lentiviral Activation Particles (h) - sc-411426-LAC from Santa Cruz Biotechnology
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RCL1 Lentiviral Activation Particles (h2) - sc-411426-LAC-2 from Santa Cruz Biotechnology
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RCL1 siRNA (h) - sc-92488 from Santa Cruz Biotechnology
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RCL1 shRNA Plasmid (h) - sc-92488-SH from Santa Cruz Biotechnology
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RCL1 shRNA (h) Lentiviral Particles - sc-92488-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU129671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18099 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18099 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06822 from Sigma-Aldrich
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RCL1 siRNA (Human) - CRH6869 from Cohesion Biosciences
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RCL1 - MBS8202042 from MyBioSource
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shRNA set against Human RCL1 (NM_005772.3) - SHH391300 from Creative biogene
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shRNA set against Human RCL1(NM_005772.3) - SHR173508 from Creative biogene
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RCL1 shRNA Plasmid (Human) - CHH6869 from Cohesion Biosciences
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RCL1 miRNA 3'UTR clone - MiUTR3H-11851 from Creative biogene
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