| Gene Symbol |
SLC20A1
|
| Entrez Gene |
6574
|
| Alt Symbol |
GLVR1, Glvr-1, PIT1, PiT-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 20 (phosphate transporter), member 1
|
| Other Description |
gibbon ape leukemia virus receptor 1|leukemia virus receptor 1 homolog|sodium-dependent phosphate transporter 1|solute carrier family 20 member 1
|
| Swissprots |
Q8WUM9 Q08344 Q6DHX8 Q9UQ82
|
| Accessions |
AAY14922 ABS82764 EAW73597 EAW73598 EAW73599 Q8WUM9 AK123420 BAG53902 AK312738 BAG35609 BC019944 AAH19944 BC075818 AAH75818 BX647555 DB086768 DQ893562 ABM84488 DQ894238 ABM85164 L20859 AAA52572 XM_005263743 XP_005263800 XM_011511686 XP_011509988 NM_005415 NP_005406
|
| Function |
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). {ECO:0000269|PubMed:11009570, ECO:0000269|PubMed:12097582, ECO:0000269|PubMed:1309898, ECO:0000269|PubMed:1531369, ECO:0000269|PubMed:2078500, ECO:0000269|PubMed:7929240, ECO:0000269|PubMed:7966619, ECO:0000269|PubMed:8041748}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:2078500}.
|