MOGAT3

Gene Symbol MOGAT3
Entrez Gene 346606
Alt Symbol DC7, DGAT2L7, MGAT3
Species Human
Gene Type protein-coding
Description monoacylglycerol O-acyltransferase 3
Other Description 2-acylglycerol O-acyltransferase 3|acyl coenzyme A:monoacylglycerol acyltransferase 3|acyl-CoA:monoacylglycerol acyltransferase 3|diacylglycerol O-acyltransferase candidate 7|diacylglycerol acyltransferase 2-like protein 7
Swissprots Q496A8 Q496A6 Q9UDW7 Q496A7 Q86VF5
Accessions AAD45832 CBF67541 CBF90900 CBU92414 CBV04420 EAW50203 EAW50204 Q86VF5 AY229854 AAO63579 AY358200 AAQ88567 BC100953 AAI00954 BC100954 AAI00955 BC100955 AAI00956 BE042458 XM_005250309 XP_005250366 XM_011516126 XP_011514428 XM_011516127 XP_011514429 NM_001287147 NP_001274076 NM_178176 NP_835470
Function Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. {ECO:0000269|PubMed:12618427}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver. {ECO:0000269|PubMed:12618427}.
Top Pathways Fat digestion and absorption, Glycerolipid metabolism

MGAT3 CRISPR/Cas9 KO Plasmid (h) - sc-415617 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 HDR Plasmid (h) - sc-415617-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 Double Nickase Plasmid (h) - sc-415617-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 Double Nickase Plasmid (h2) - sc-415617-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 CRISPR Activation Plasmid (h) - sc-415617-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 CRISPR Activation Plasmid (h2) - sc-415617-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 Lentiviral Activation Particles (h) - sc-415617-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 Lentiviral Activation Particles (h2) - sc-415617-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 siRNA (h) - sc-44469 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MGAT3 shRNA Plasmid (h) - sc-44469-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MGAT3 shRNA (h) Lentiviral Particles - sc-44469-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MOGAT3 RNAi - H00346606-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU012791 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14465 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14465 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00494 from Sigma-Aldrich

Category miRNA

MOGAT3 siRNA (Human) - CRJ7486 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MOGAT3 (NM_178176.2) - SHH343440 from Creative biogene

Category siRNA
Species Reactivities Human

MGAT3 CRISPR/Cas9 KO Plasmid (h2) - sc-415617-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGAT3 HDR Plasmid (h2) - sc-415617-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human MOGAT3 siRNA - orb277987 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MOGAT3 shRNA Plasmid (Human) - CHJ7486 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MOGAT3 miRNA 3'UTR clone - MiUTR1H-06380 from Creative biogene

Species Reactivities Human
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