| Gene Symbol |
TROVE2
|
| Entrez Gene |
6738
|
| Alt Symbol |
RO60, RORNP, SSA2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TROVE domain family, member 2
|
| Other Description |
60 kDa SS-A/Ro ribonucleoprotein|60 kDa ribonucleoprotein Ro|Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro)|gastric cancer multi-drug resistance protein|sjoegren syndrome type A antigen
|
| Swissprots |
Q9H1W6 Q5LJA0 B2RBB9 P10155 Q86WL4 Q5LJ99 Q92787 Q86WL3 Q5LJ98
|
| Accessions |
AAB81552 AAB81553 EAW91239 EAW91240 EAW91241 EAW91242 EAW91243 EAW91244 EAW91245 EAW91246 EAW91247 P10155 AI433657 AK314594 BAG37166 AY205314 AAO47001 AY205315 AAO47002 BC036658 AAH36658 BI560207 BQ227323 BX394323 CR936683 CX761715 DA518443 DQ891526 ABM82452 DQ894716 ABM85642 J04137 AAA35493 M25077 AAA35532 S57803 S57805 XM_006711495 XP_006711558 XM_006711496 XP_006711559 XM_006711497 XP_006711560 XM_011509920 XP_011508222 XM_011509921 XP_011508223 XM_011509922 XP_011508224 NM_001042369 NP_001035828 NM_001042370 NP_001035829 NM_001173524 NP_001166995 NM_001173525 NP_001166996 NM_004600 NP_004591 NR_033393
|
| Function |
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. {ECO:0000269|PubMed:18056422}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
|
| Top Pathways |
Systemic lupus erythematosus
|