| Gene Symbol | Hyal2 |
|---|---|
| Entrez Gene | 15587 |
| Alt Symbol | AI256841, AU020858, AW555733 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | hyaluronoglucosaminidase 2 |
| Other Description | hyal-2|hyaluronidase 2|hyaluronidase-2|hyaluronoglucosaminidase-2 |
| Swissprots | Q99MT0 Q99MS9 O35631 O35632 |
| Accessions | CAA03889 EDL21201 EDL21202 O35632 AF302843 AAK28481 AF302844 AAK28482 AF422177 AAL17823 AF535140 AAO49503 AJ000059 CAA03888 AK080146 AK087358 BAC39851 AK088806 BAC40583 AK133886 BAE21913 BC060047 XM_006511643 XP_006511706 XM_006511644 XP_006511707 XM_006511645 XP_006511708 NM_010489 NP_034619 |
| Function | Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
| Tissue Specificity | Widely expressed. In the brain, expressed during embryonic stages but expression decreases after birth and is barely detectable in adult brain. {ECO:0000269|PubMed:9790770}. |
| Top Pathways | Glycosaminoglycan degradation |