Gene Symbol | DCP1B |
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Entrez Gene | 196513 |
Alt Symbol | DCP1, hDcp1b |
Species | Human |
Gene Type | protein-coding |
Description | decapping mRNA 1B |
Other Description | DCP1 decapping enzyme homolog B|decapping enzyme hDcp1b|mRNA-decapping enzyme 1B |
Swissprots | Q96MZ8 Q86XH9 B4DRD1 Q96BP8 Q8IZD4 |
Accessions | EAW88915 EAW88916 Q8IZD4 AK056200 BAB71118 AK299203 BAG61243 AK301109 BAG62708 AK310475 AW204088 AY146652 AAN62764 BC015368 AAH15368 BC043437 AAH43437 XM_011520927 XP_011519229 XM_011520928 XP_011519230 NM_152640 NP_689853 |
Function | May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15067023}. Nucleus {ECO:0000250}. |
Top Pathways | RNA degradation |
hDcp1b CRISPR/Cas9 KO Plasmid (h) - sc-414965 from Santa Cruz Biotechnology
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hDcp1b HDR Plasmid (h) - sc-414965-HDR from Santa Cruz Biotechnology
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hDcp1b Double Nickase Plasmid (h) - sc-414965-NIC from Santa Cruz Biotechnology
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hDcp1b Double Nickase Plasmid (h2) - sc-414965-NIC-2 from Santa Cruz Biotechnology
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hDcp1b CRISPR Activation Plasmid (h) - sc-414965-ACT from Santa Cruz Biotechnology
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hDcp1b CRISPR Activation Plasmid (h2) - sc-414965-ACT-2 from Santa Cruz Biotechnology
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hDcp1b Lentiviral Activation Particles (h) - sc-414965-LAC from Santa Cruz Biotechnology
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hDcp1b Lentiviral Activation Particles (h2) - sc-414965-LAC-2 from Santa Cruz Biotechnology
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hDcp1b siRNA (h) - sc-105444 from Santa Cruz Biotechnology
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hDcp1b shRNA Plasmid (h) - sc-105444-SH from Santa Cruz Biotechnology
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hDcp1b shRNA (h) Lentiviral Particles - sc-105444-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU005791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6996 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6996 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01434 from Sigma-Aldrich
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DCP1B siRNA (Human) - CRJ6181 from Cohesion Biosciences
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DCP1B - MBS8219429 from MyBioSource
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DCP1B shRNA Plasmid (Human) - CHJ6181 from Cohesion Biosciences
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