HLA-DOA

Gene Symbol HLA-DOA
Entrez Gene 3111
Alt Symbol HLA-DNA, HLA-DZA, HLADZ
Species Human
Gene Type protein-coding
Description major histocompatibility complex, class II, DO alpha
Other Description HLA class II histocompatibility antigen, DO alpha chain|HLA-D0-alpha|MHC DN-alpha|MHC DZ alpha|MHC class II antigen DOA|lymphocyte antigen|major histocompatibility complex, class II, DN alpha
Swissprots Q9TQD1 Q9TQD3 Q9TQD0 Q58HU1 Q9TQD2 Q9TQC6 Q5STC7 Q9TQC8 Q9TQC7 P06340 Q58HU0 Q9TQC9
Accessions AAA36254 AHW47931 AHW47948 AHW47965 AHW47982 BAA81787 BAA81788 BAA81789 BAA81790 BAA81791 BAA81792 BAA81793 BAA81794 CAA26635 CAB03594 CAC70064 EAX03667 EAX03668 P06340 AJ420585 AK290714 BAF83403 AK301404 BAG62939 AK310153 AK313551 BAG36327 AY947479 AAX49509 AY947480 AAX49510 AY947481 AAX49511 AY947482 AAX49512 BC013183 AAH13183 DQ891048 ABM81974 DQ894226 ABM85152 M26039 AAA59716 M29335 AAA36253 M31525 AAA60075 M38054 M38056 AAA35992 XM_005249047 XP_005249104 XM_005272804 XP_005272861 XM_005274951 XP_005275008 XM_005275106 XP_005275163 XM_005275243 XP_005275300 XM_005275383 XP_005275440 XM_005275540 XP_005275597 XM_006715076 XP_006715139 XM_006725483 XP_006725546 XM_006725697 XP_006725760 XM_006725815 XP_006725878 XM_006725906 XP_006725969 XM_006725996 XP_006726059 XM_006726086 XP_006726149 XM_011514558 XP_011512860 XM_011547240 XP_011545542 XM_011548043 XP_011546345 XM_011548231 XP_011546533 XM_011548423 XP_011546725 NM_002119 NP_002110
Function Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Subcellular Location Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
Top Pathways Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection

HLA-DOα (G-15) - sc-103546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HLA-DOα (Q-13) - sc-103547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HLA-DOα (W-13) - sc-103548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HLA-DOA antibody - ab74981 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HLA-DOA antibody (ab74981) at 1/500 dilutionLane 1 : extracts from COLO cellsLane 2 : extracts from COLO cells with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-HLA-DOA antibody - ab67079 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HLA-DOA antibody (ab67079) at 1/500 dilutionLane 1 : HLA-DOA transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-HLA-DOA antibody - ab171906 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HLA-DOA antibody (ab171906) at 1 µg/mlLane 1 : HLA-DOA transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-HLA-DOA antibody - N-terminal - ab180071 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HLA-DOA antibody - N-terminal (ab180071) at 1/1000 dilution + HL-60 cell line lysates at 35 µg

Anti-HLA-DOA Antibody - LS-C311219 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HLA-DOA Antibody - LS-C308255 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HLA-DOA Antibody - LS-C311419 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DOA Antibody (aa71-120) - LS-C120041 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO cells, using HLA-DOA Antibody. The lane on the right is treated with the synthesized peptide.

Anti-HLA-DOA Antibody (aa31-59) - LS-C203820 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HLA-DOA Antibody western blot of HL-60 cell line lysates (35 ug/lane). The HLA-DOA antibody detected the HLA-DOA protein (arrow).

Anti-HLA-DOA Antibody (Val111) - LS-C177380 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of HLA-DO (V111) pAb in paraffin-embedded human breast carcinoma tissue.

HLA DOA Antibody - NBP1-91993 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HLA DOA Antibody [NBP1-91993] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

HLA DOA Antibody - NBP1-30512 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HLA DOA Antibody [NBP1-30512] - Western blot (WB) analysis of HLA DOA antibody in extracts from COLO cells.

HLA DOA Antibody - H00003111-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HLA DOA Antibody [H00003111-B01P] - Analysis of HLA-DOA expression in transfected 293T cell line by HLA-DOA polyclonal antibody. Lane 1: HLA-DOA transfected lysate(27.61 KDa). Lane 2: Non-transfected lysate.

HLA DOA Antibody - H00003111-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HLA DOA Antibody [H00003111-D01P] - Analysis of HLA-DOA expression in transfected 293T cell line by HLA-DOA polyclonal antibody.Lane 1: HLA-DOA transfected lysate(27.60 KDa).Lane 2: Non-transfected lysate.

HLA DOA Antibody - H00003111-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HLA DOA Antibody [H00003111-B01] - analysis of HLA-DOA expression in transfected 293T cell line by HLA-DOA MaxPab polyclonal antibody (B01). Lane 1: HLA-DOA transfected lysate (27.61 KDa). Lane 2: Non-transfected lysate.

HLA DOA Antibody - H00003111-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

HLA DOA Antibody - H00003111-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HLA DOA Antibody [H00003111-B02] - analysis of HLA-DOA expression in transfected 293T cell line by HLA-DOA MaxPab polyclonal antibody (B02). Lane 1: HLA-DOA transfected lysate (27.60 KDa). Lane 2: Non-transfected lysate.

HLA DOA Antibody - H00003111-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HLA-DOA antibody produced in mouse - SAB1405939 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HLA-DOA: <B>Cat. No. SAB1405939</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~27.6 kDa using HLA~DOA transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-HLA-DOA antibody produced in rabbit - SAB4501398 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HLA-DOA: <B>Cat. No. SAB4501398</B>: Immunoblotting analysis of extracts from COLO cells, using Anti-HLA-DOA antibody. The lane on the left was treated with the Anti-HLA-DOA antibody. The lane on the right (negative control) was treated with both Anti-HLA-DOA antibody and the synthesized immunogen peptide.

Anti-HLA-DOA antibody produced in rabbit - HPA045038 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HLA-DOA: <B>Cat. No. HPA045038</B>: Immunohistochemical staining of human tonsil shows strong granular cytoplasmic positivity in non-germinal center cells.

Anti-HLA-DOA antibody produced in rabbit - SAB1401175 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-HLA-DOA, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401175</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~27.60 kDa using HLA-DOA transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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