Gene Symbol | Mc2r |
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Entrez Gene | 17200 |
Alt Symbol | ACTH-R, ACTHR, MC2-R |
Species | Mouse |
Gene Type | protein-coding |
Description | melanocortin 2 receptor |
Other Description | ACTH receptor|adrenocorticotropic hormone receptor|adrenocorticotropin receptor|melanocortin receptor 2 |
Swissprots | Q64326 |
Accessions | AAB34919 BAA06722 EDL09606 EDL09607 EDL09608 EDL09609 Q64326 AF510739 AK033100 BAC28151 BC139210 AAI39211 BC139211 AAI39212 D85688 D85689 DQ294344 NM_001271716 NP_001258645 NM_001271717 NP_001258646 NM_001301372 NP_001288301 NM_008560 NP_032586 |
Function | Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
MC2-R CRISPR/Cas9 KO Plasmid (m) - sc-421584 from Santa Cruz Biotechnology
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MC2-R HDR Plasmid (m) - sc-421584-HDR from Santa Cruz Biotechnology
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MC2-R Double Nickase Plasmid (m) - sc-421584-NIC from Santa Cruz Biotechnology
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MC2-R Double Nickase Plasmid (m2) - sc-421584-NIC-2 from Santa Cruz Biotechnology
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MC2-R CRISPR Activation Plasmid (m) - sc-421584-ACT from Santa Cruz Biotechnology
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MC2-R CRISPR Activation Plasmid (m2) - sc-421584-ACT-2 from Santa Cruz Biotechnology
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MC2-R Lentiviral Activation Particles (m) - sc-421584-LAC from Santa Cruz Biotechnology
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MC2-R Lentiviral Activation Particles (m2) - sc-421584-LAC-2 from Santa Cruz Biotechnology
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MC2-R siRNA (m) - sc-40110 from Santa Cruz Biotechnology
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MC2-R shRNA Plasmid (m) - sc-40110-SH from Santa Cruz Biotechnology
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MC2-R shRNA (m) Lentiviral Particles - sc-40110-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU020421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN35349 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35349 from Sigma-Aldrich
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MC2R siRNA (Mouse) - CRM2481 from Cohesion Biosciences
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shRNA set against Mouse MC2R (NM_008560.2) - SHH339043 from Creative biogene
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shRNA set against Mouse Mc2r(NM_008560.2) - SHH180281 from Creative biogene
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Mouse MC2R siRNA - orb281957 from Biorbyt
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MC2R shRNA Plasmid (Mouse) - CHM2481 from Cohesion Biosciences
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MC2R miRNA 3'UTR clone - MiUTR1M-06987 from Creative biogene
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