Gene Symbol | CDH13 |
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Entrez Gene | 1012 |
Alt Symbol | CDHH, P105 |
Species | Human |
Gene Type | protein-coding |
Description | cadherin 13 |
Other Description | H-cadherin (heart)|T-cad|T-cadherin|cadherin 13, H-cadherin (heart)|cadherin-13|heart cadherin |
Swissprots | C9JRI6 A8W477 A8W476 P55290 Q6GTW4 B7Z590 J3KN62 Q8TBX3 |
Accessions | BAA32411 EAW95515 P55290 AI802411 AK294277 BAH11722 AK295886 BAH12213 AK298612 BAH12826 AK304592 BAH14221 AK304733 BAH14247 AK307862 AU123178 BC012615 BC028624 AAH28624 BC030653 AAH30653 BG911233 BI756586 BU162665 BU627784 CA445317 CB321814 CF618908 CK725094 CN263227 CV024366 DA561809 DA685616 DB003683 DC376661 DQ891713 ABM82639 DQ894890 ABM85816 EU190357 ABW97440 EU190358 ABW97441 L34058 AAA35624 R41787 U59288 AAB18911 XM_011522804 XP_011521106 XM_011522805 XP_011521107 NM_001220488 NP_001207417 NM_001220489 NP_001207418 NM_001220490 NP_001207419 NM_001220491 NP_001207420 NM_001220492 NP_001207421 NM_001257 NP_001248 |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. {ECO:0000269|PubMed:10737605}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord. {ECO:0000269|PubMed:10737605, ECO:0000269|PubMed:8673923}. |
T-cadherin CRISPR/Cas9 KO Plasmid (h) - sc-416752 from Santa Cruz Biotechnology
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T-cadherin HDR Plasmid (h) - sc-416752-HDR from Santa Cruz Biotechnology
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T-cadherin Double Nickase Plasmid (h) - sc-416752-NIC from Santa Cruz Biotechnology
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T-cadherin Double Nickase Plasmid (h2) - sc-416752-NIC-2 from Santa Cruz Biotechnology
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T-cadherin CRISPR Activation Plasmid (h) - sc-416752-ACT from Santa Cruz Biotechnology
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T-cadherin CRISPR Activation Plasmid (h2) - sc-416752-ACT-2 from Santa Cruz Biotechnology
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T-cadherin Lentiviral Activation Particles (h) - sc-416752-LAC from Santa Cruz Biotechnology
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T-cadherin Lentiviral Activation Particles (h2) - sc-416752-LAC-2 from Santa Cruz Biotechnology
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T-cadherin siRNA (h) - sc-43015 from Santa Cruz Biotechnology
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T-cadherin shRNA Plasmid (h) - sc-43015-SH from Santa Cruz Biotechnology
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T-cadherin shRNA (h) Lentiviral Particles - sc-43015-V from Santa Cruz Biotechnology
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Cadherin-13 RNAi - H00001012-R01 from Novus Biologicals
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MISSION® esiRNA - EHU025411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5810 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5810 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12692 from Sigma-Aldrich
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CDH13 siRNA (Human) - CRH0725 from Cohesion Biosciences
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CDH13 - MBS8204798 from MyBioSource
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shRNA set against Human CDH13 (NM_001257.4) - SHH260161 from Creative biogene
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Human CDH13 siRNA - orb261227 from Biorbyt
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CDH13 shRNA Plasmid (Human) - CHH0725 from Cohesion Biosciences
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CDH13 miRNA 3'UTR clone - MiUTR3H-04077 from Creative biogene
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