| Gene Symbol |
KCNJ15
|
| Entrez Gene |
3772
|
| Alt Symbol |
IRKK, KIR1.3, KIR4.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, inwardly rectifying subfamily J, member 15
|
| Other Description |
ATP-sensitive inward rectifier potassium channel 15|inward rectifier K(+) channel Kir1.3|inward rectifier K(+) channel Kir4.2|inward rectifier K+ channel KIR4.2|potassium channel, inwardly rectifying subfamily J member 15|potassium inwardly-rectifying channel, subfamily J, member 15
|
| Swissprots |
Q99712 Q96L28 D3DSH5 Q99446 O00564
|
| Accessions |
EAX09683 EAX09684 EAX09685 Q99712 AI344546 AI453386 AK092958 AK292812 BAF85501 BC013327 AAH13327 BI832561 D87291 BAA13326 DA632853 DA670230 DA673158 DA675388 DA968871 DB008463 DB232867 DQ896861 ABM87860 U73191 AAC50922 Y10745 CAA71734 Y13895 Y13896 XM_005260975 XP_005261032 XM_006724002 XP_006724065 XM_011529560 XP_011527862 XM_011529561 XP_011527863 NM_001276435 NP_001263364 NM_001276436 NP_001263365 NM_001276437 NP_001263366 NM_001276438 NP_001263367 NM_001276439 NP_001263368 NM_002243 NP_002234 NM_170736 NP_733932 NM_170737 NP_733933
|
| Function |
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Top Pathways |
Gastric acid secretion
|