Gene Symbol | LYRM7 |
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Entrez Gene | 90624 |
Alt Symbol | C5orf31, MC3DN8, MZM1L |
Species | Human |
Gene Type | protein-coding |
Description | LYR motif containing 7 |
Other Description | LYR motif-containing protein 7|Lyrm7 homolog|complex III assembly factor LYRM7 |
Swissprots | Q5U5X0 A8MPQ9 Q86Y68 |
Accessions | EAW62375 Q5U5X0 AK000803 AK056991 BC022429 BC037930 AAH37930 BC047079 AAH47079 BG714193 BI601105 BI667583 DA996312 NM_001293735 NP_001280664 NM_181705 NP_859056 NR_121658 |
Function | Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. {ECO:0000269|PubMed:23168492}. |
Subcellular Location | Mitochondrion matrix {ECO:0000269|PubMed:23168492}. |
LYRM7 CRISPR/Cas9 KO Plasmid (h) - sc-416772 from Santa Cruz Biotechnology
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LYRM7 HDR Plasmid (h) - sc-416772-HDR from Santa Cruz Biotechnology
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LYRM7 Double Nickase Plasmid (h) - sc-416772-NIC from Santa Cruz Biotechnology
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LYRM7 Double Nickase Plasmid (h2) - sc-416772-NIC-2 from Santa Cruz Biotechnology
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LYRM7 CRISPR Activation Plasmid (h) - sc-416772-ACT from Santa Cruz Biotechnology
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LYRM7 CRISPR Activation Plasmid (h2) - sc-416772-ACT-2 from Santa Cruz Biotechnology
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LYRM7 Lentiviral Activation Particles (h) - sc-416772-LAC from Santa Cruz Biotechnology
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LYRM7 Lentiviral Activation Particles (h2) - sc-416772-LAC-2 from Santa Cruz Biotechnology
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LYRM7 siRNA (h) - sc-91683 from Santa Cruz Biotechnology
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LYRM7 shRNA Plasmid (h) - sc-91683-SH from Santa Cruz Biotechnology
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LYRM7 shRNA (h) Lentiviral Particles - sc-91683-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12868 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12868 from Sigma-Aldrich
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LYRM7 siRNA (Human) - CRJ3967 from Cohesion Biosciences
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shRNA set against Human LYRM7 (NM_181705.2) - SHH336175 from Creative biogene
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shRNA set against Human LYRM7(NM_181705.2) - SHH168869 from Creative biogene
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Human LYRM7 siRNA - orb274468 from Biorbyt
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LYRM7 shRNA Plasmid (Human) - CHJ3967 from Cohesion Biosciences
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LYRM7 miRNA 3'UTR clone - MiUTR1H-05981 from Creative biogene
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