| Gene Symbol |
CDIP1
|
| Entrez Gene |
29965
|
| Alt Symbol |
C16orf5, CDIP, I1, LITAFL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cell death-inducing p53 target 1
|
| Other Description |
LITAF-like protein|cell death inducing protein|cell death involved p53-target|cell death-inducing p53-target protein 1|cell death-inducing protein|lipopolysaccharide-induced tumor necrosis factor-alpha-like protein|transmembrane protein I1
|
| Swissprots |
D3DUD6 Q9P112 B4DY75 Q9H0Q4 Q96ID8 Q9H305 B4DFU1 A8K7M1
|
| Accessions |
EAW85291 EAW85292 EAW85293 EAW85294 EAW85295 EAW85296 EAW85297 EAW85298 Q9H305 AF131218 AAF26619 AF195661 AAG35583 AK292036 BAF84725 AK294257 BAG57552 AK302297 BAG63637 AK307067 AK308532 AK311295 AL136698 CAB66633 AL833853 CAD38712 BC002882 AAH02882 BC007604 AAH07604 CR533446 CAG38477 DA055704 DQ167023 AAZ94626 JF432275 ADZ15492 XM_011522468 XP_011520770 NM_001199054 NP_001185983 NM_001199055 NP_001185984 NM_001199056 NP_001185985 NM_013399 NP_037531
|
| Function |
Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner. {ECO:0000269|PubMed:17599062}.
|
| Tissue Specificity |
Highly expressed in brain. Expressed at lower level in heart, skeletal muscle, kidney, pancreas and liver. Weakly or not expressed in placenta and lung. {ECO:0000269|PubMed:10570909}.
|
![Western Blot: CDIP Overexpression Lysate (Adult Normal) [NBL1-08215] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDIP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/19354_CDIP%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-08215-img0002.jpg)