UPP1

Gene Symbol UPP1
Entrez Gene 7378
Alt Symbol UDRPASE, UP, UPASE, UPP
Species Human
Gene Type protein-coding
Description uridine phosphorylase 1
Other Description UPase 1|urdPase 1
Swissprots Q15362 Q16831 D3DVM4
Accessions EAW60993 EAW60994 EAW60995 EAW60996 Q16831 AK096167 AK297863 BAG60192 BC001405 AAH01405 BC007348 AAH07348 BC047030 AAH47030 BC053592 AAH53592 BE622095 BE901028 BF027447 BF668084 BI199725 BM544854 BM557506 BT006699 AAP35345 BU528636 CD105246 X90858 CAA62369 XM_005249838 XP_005249895 XM_006715771 XP_006715834 XM_011515512 XP_011513814 XM_011515513 XP_011513815 XM_011515514 XP_011513816 XM_011515515 XP_011513817 XM_011515516 XP_011513818 NM_181597 NM_001287426 NP_001274355 NM_001287428 NP_001274357 NM_001287429 NP_001274358 NM_001287430 NP_001274359 NM_003364 NP_003355 NR_109837
Function Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Top Pathways Drug metabolism - other enzymes, Pyrimidine metabolism