Gene Symbol | UPP1 |
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Entrez Gene | 7378 |
Alt Symbol | UDRPASE, UP, UPASE, UPP |
Species | Human |
Gene Type | protein-coding |
Description | uridine phosphorylase 1 |
Other Description | UPase 1|urdPase 1 |
Swissprots | Q15362 Q16831 D3DVM4 |
Accessions | EAW60993 EAW60994 EAW60995 EAW60996 Q16831 AK096167 AK297863 BAG60192 BC001405 AAH01405 BC007348 AAH07348 BC047030 AAH47030 BC053592 AAH53592 BE622095 BE901028 BF027447 BF668084 BI199725 BM544854 BM557506 BT006699 AAP35345 BU528636 CD105246 X90858 CAA62369 XM_005249838 XP_005249895 XM_006715771 XP_006715834 XM_011515512 XP_011513814 XM_011515513 XP_011513815 XM_011515514 XP_011513816 XM_011515515 XP_011513817 XM_011515516 XP_011513818 NM_181597 NM_001287426 NP_001274355 NM_001287428 NP_001274357 NM_001287429 NP_001274358 NM_001287430 NP_001274359 NM_003364 NP_003355 NR_109837 |
Function | Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. |
Top Pathways | Drug metabolism - other enzymes, Pyrimidine metabolism |
UPase CRISPR/Cas9 KO Plasmid (h) - sc-411050 from Santa Cruz Biotechnology
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UPase HDR Plasmid (h) - sc-411050-HDR from Santa Cruz Biotechnology
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UPase Double Nickase Plasmid (h) - sc-411050-NIC from Santa Cruz Biotechnology
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UPase Double Nickase Plasmid (h2) - sc-411050-NIC-2 from Santa Cruz Biotechnology
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UPase CRISPR Activation Plasmid (h) - sc-411050-ACT from Santa Cruz Biotechnology
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UPase CRISPR Activation Plasmid (h2) - sc-411050-ACT-2 from Santa Cruz Biotechnology
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UPase Lentiviral Activation Particles (h) - sc-411050-LAC from Santa Cruz Biotechnology
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UPase Lentiviral Activation Particles (h2) - sc-411050-LAC-2 from Santa Cruz Biotechnology
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UPase siRNA (h) - sc-41087 from Santa Cruz Biotechnology
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UPase shRNA Plasmid (h) - sc-41087-SH from Santa Cruz Biotechnology
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UPase shRNA (h) Lentiviral Particles - sc-41087-V from Santa Cruz Biotechnology
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Uridine Phosphorylase 1/UPP1 RNAi - H00007378-R02 from Novus Biologicals
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Uridine Phosphorylase 1/UPP1 RNAi - H00007378-R01 from Novus Biologicals
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MISSION® esiRNA - EHU093321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22526 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22526 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02898 from Sigma-Aldrich
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UPP1 siRNA (Human) - CRH5047 from Cohesion Biosciences
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UPP1 - MBS8228372 from MyBioSource
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shRNA set against Human UPP1 (NM_181597.1) - SHH440844 from Creative biogene
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shRNA set against Human UPP1(NM_003364.2) - SHL115686 from Creative biogene
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UPP1 shRNA Plasmid (Human) - CHH5047 from Cohesion Biosciences
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UPP1 miRNA 3'UTR clone - MiUTR1H-11030 from Creative biogene
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UPP1 miRNA 3'UTR clone - MiUTR3H-02381 from Creative biogene
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