Gene Symbol | POLR1C |
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Entrez Gene | 9533 |
Alt Symbol | RPA39, RPA40, RPA5, RPAC1, TCS3 |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (RNA) I polypeptide C, 30kDa |
Other Description | AC40|DNA-directed RNA polymerase I subunit C|DNA-directed RNA polymerases I and III 40 kDa polypeptide|DNA-directed RNA polymerases I and III subunit RPAC1|RNA polymerases I and III subunit AC1|RPC40 |
Swissprots | O15160 Q5JTE3 O75395 |
Accessions | CCQ43287 EAX04204 EAX04205 EAX04208 O15160 AF008442 AAC14354 AF047441 AAC39892 AK293561 BAG57033 BC008118 AAH08118 BC008863 AAH08863 BM828768 BQ575535 HQ448228 ADQ32708 XM_005249491 XP_005249548 XM_011515000 XP_011513302 NM_203290 NP_976035 NM_004875 |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism |
Human POLR1C full length protein - ab132610 from Abcam
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Human POLR1C full length protein - ab180317 from Abcam
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POLR1C / RPA39 Antibody Blocking Peptide - LS-E7139 from LifeSpan Bioscience
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POLR1C Recombinant Protein - H00009533-P01 from Novus Biologicals
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POLR1C-Antibody-Center-Blocking-Peptide - BP2839c from Abgent, a WuXi AppTec company
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POLR1C-Antibody-C-term-Blocking-Peptide - BP2839b from Abgent, a WuXi AppTec company
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POLR1C protein (His tag) - 80R-3886 from Fitzgerald
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POLR1C Blocking Peptide - abx063596 from Abbexa
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POLR1C (1-349, His-tag) - AR51573PU-N from Acris Antibodies
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POLR1C (1-349, His-tag) - AR51573PU-S from Acris Antibodies
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POLR1C - H00009533-P01-10 from Acris Antibodies
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POLR1C - H00009533-P01-25 from Acris Antibodies
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POLR1C, 1-349aa, Human, His tag, E.coli - 01-P2753 from ARP American Research Products
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POLR1C fusion protein - Ag8746 from Proteintech Group
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Recombinant Human POLR1C, His-tagged - POLR1C-28614TH from Creative Biomart
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Recombinant Human POLR1C, His-tagged - POLR1C-260H from Creative Biomart
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Recombinant Human POLR1C, GST-tagged - POLR1C-1838H from Creative Biomart
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POLR1C Blocking Peptide - CBP2402 from Cohesion Biosciences
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POLR1C Peptide - BS5916P from Bioworld Technology
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Recombinant Human DNA-directed RNA polymerases I and III subunit RPAC1(POLR1C) - CSB-YP018324HU CSB-EP018324HU CSB-BP018324HU CSB-MP018324HU from Cusabio
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POLR1C, 1-349aa, Human, His tag, E.coli - ATGP2753 from ATGen
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POLR1C (transcript variant 1) - TP303486 from Acris Antibodies
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POLR1C, Recombinant Protein - MBS205665 from MyBioSource
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POLR1C Protein - NBP1-87114PEP from Novus Biologicals
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Human POLR1C protein - orb260023 from Biorbyt
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