Gene Symbol | ALDH1A3 |
---|---|
Entrez Gene | 220 |
Alt Symbol | ALDH1A6, ALDH6, MCOP8, RALDH3 |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 1 family, member A3 |
Other Description | acetaldehyde dehydrogenase 6|aldehyde dehydrogenase 6|aldehyde dehydrogenase family 1 member A3|retinaldehyde dehydrogenase 3 |
Swissprots | Q6NT64 P47895 |
Accessions | EAX02281 EAX02282 EAX02283 P47895 AK056534 AK302607 BAG63855 AK303441 BAG64488 AK312303 BAG35229 AL110109 BC009245 BC069274 AAH69274 BC101605 AAI01606 BC117365 AAI17366 BX538027 CAD97973 DB480234 EU831943 ACE87384 EU832038 ACE86700 HG507539 HG507540 HG507541 U07919 AAA79036 NM_000693 NP_000684 NM_001293815 NP_001280744 NM_001037224 |
Function | Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney. |
Top Pathways | Chemical carcinogenesis, Glycolysis / Gluconeogenesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Tyrosine metabolism |
ALDH1A3 CRISPR/Cas9 KO Plasmid (h) - sc-401630 from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 HDR Plasmid (h) - sc-401630-HDR from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 Double Nickase Plasmid (h) - sc-401630-NIC from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 Double Nickase Plasmid (h2) - sc-401630-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 CRISPR Activation Plasmid (h) - sc-401630-ACT from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 CRISPR Activation Plasmid (h2) - sc-401630-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 Lentiviral Activation Particles (h) - sc-401630-LAC from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 Lentiviral Activation Particles (h2) - sc-401630-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 siRNA (h) - sc-43611 from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 shRNA Plasmid (h) - sc-43611-SH from Santa Cruz Biotechnology
|
||||||||
ALDH1A3 shRNA (h) Lentiviral Particles - sc-43611-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU060321 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1783 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1783 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10507 from Sigma-Aldrich
|
||||||||
ALDH1A3 siRNA (Human) - CRH0155 from Cohesion Biosciences
|
||||||||
ALDH1A3 - MBS8236833 from MyBioSource
|
||||||||
shRNA set against Human ALDH1A3 (NM_000693.2) - SHH234814 from Creative biogene
|
||||||||
shRNA set against Human ALDH1A3(NM_000693.2) - SHG052363 from Creative biogene
|
||||||||
ALDH1A3 shRNA Plasmid (Human) - CHH0155 from Cohesion Biosciences
|
||||||||
ALDH1A3 miRNA 3'UTR clone - MiUTR1H-00286 from Creative biogene
|