Gene Symbol | SLC25A5 |
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Entrez Gene | 292 |
Alt Symbol | 2F1, AAC2, ANT2, T2, T3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 |
Other Description | ADP,ATP carrier protein 2|ADP,ATP carrier protein, fibroblast isoform|ADP/ATP carrier protein|ADP/ATP translocase 2|ANT 2|adenine nucleotide translocator 2 (fibroblast)|solute carrier family 25 member 5 |
Swissprots | O43350 P05141 B2RCV1 |
Accessions | AAA51737 AAB39266 AAB96347 EAW89868 EAW89869 EAW89870 P05141 AK315292 BAG37698 BC056160 AAH56160 BC068199 AAH68199 BQ223988 DB555059 DR759917 HQ448108 ADQ32589 J02683 AAA35579 J03591 AAA36749 NM_001152 NP_001143 |
Function | Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. {ECO:0000269|PubMed:20797633}. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
Top Pathways | Huntington's disease, Calcium signaling pathway, HTLV-I infection, cGMP-PKG signaling pathway |
ANT2 CRISPR/Cas9 KO Plasmid (h) - sc-400680 from Santa Cruz Biotechnology
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ANT2 HDR Plasmid (h) - sc-400680-HDR from Santa Cruz Biotechnology
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ANT2 Double Nickase Plasmid (h) - sc-400680-NIC from Santa Cruz Biotechnology
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ANT2 Double Nickase Plasmid (h2) - sc-400680-NIC-2 from Santa Cruz Biotechnology
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ANT2 CRISPR Activation Plasmid (h) - sc-400680-ACT from Santa Cruz Biotechnology
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ANT2 CRISPR Activation Plasmid (h2) - sc-400680-ACT-2 from Santa Cruz Biotechnology
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ANT2 Lentiviral Activation Particles (h) - sc-400680-LAC from Santa Cruz Biotechnology
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ANT2 Lentiviral Activation Particles (h2) - sc-400680-LAC-2 from Santa Cruz Biotechnology
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ANT2 siRNA (h) - sc-72505 from Santa Cruz Biotechnology
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ANT2 shRNA Plasmid (h) - sc-72505-SH from Santa Cruz Biotechnology
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ANT2 shRNA (h) Lentiviral Particles - sc-72505-V from Santa Cruz Biotechnology
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Adenine Nucleotide Translocator 2 RNAi - H00000292-R01 from Novus Biologicals
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MISSION® esiRNA - EHU110021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19518 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19518 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01797 from Sigma-Aldrich
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SLC25A5 siRNA (Human) - CRH0204 from Cohesion Biosciences
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SLC25A5 - MBS8210032 from MyBioSource
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shRNA set against Human SLC25A5 (NM_001152.4) - SHH409888 from Creative biogene
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Human SLC25A5 siRNA - orb260706 from Biorbyt
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SLC25A5 shRNA Plasmid (Human) - CHH0204 from Cohesion Biosciences
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SLC25A5 miRNA 3'UTR clone - MiUTR3H-02598 from Creative biogene
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