| Gene Symbol |
ANAPC10
|
| Entrez Gene |
10393
|
| Alt Symbol |
APC10, DOC1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
anaphase promoting complex subunit 10
|
| Other Description |
anaphase-promoting complex subunit 10|cyclosome subunit 10
|
| Swissprots |
Q9UM13 Q2V500 Q9Y5R0 Q9UG51 D3DNZ7
|
| Accessions |
AAY40941 ABB96248 EAX05050 EAX05051 EAX05052 EAX05053 Q9UM13 AB012109 BAA86953 AF132794 AAD30527 AL080090 CAB45705 AV757106 BC005217 AAH05217 BF693880 BG494966 BG530912 BI488888 BU175327 BU567906 CN305215 CV023091 EU831650 ACE87250 EU831734 ACE86568 JF432741 ADZ15958 XM_011531521 XP_011529823 XM_011531522 XP_011529824 XM_011531523 XP_011529825 XM_011531524 XP_011529826 XM_011531525 XP_011529827 XM_011531526 XP_011529828 XM_011531527 XP_011529829 XM_011531528 XP_011529830 XM_011531529 XP_011529831 XM_011531530 XP_011529832 XM_011531531 XP_011529833 XM_011531532 XP_011529834 NM_001256706 NP_001243635 NM_001256707 NP_001243636 NM_001256708 NP_001243637 NM_001256709 NP_001243638 NM_001256710 NP_001243639 NM_001256711 NP_001243640 NM_001256712 NP_001243641 NM_014885 NP_055700 NR_046345
|
| Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
|
| Top Pathways |
Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection
|
