Gene Symbol | SPOCK3 |
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Entrez Gene | 50859 |
Alt Symbol | HSAJ1454, TES-3, TICN3 |
Species | Human |
Gene Type | protein-coding |
Description | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
Other Description | testican-3 |
Swissprots | B3KR67 B4DGK5 E7EP61 O75705 B4DHB4 B2R7M7 Q6UW53 F5H099 B4DHV3 Q9BQ16 Q96Q26 B4DJY3 B4DI46 |
Accessions | AAY40960 AAY40993 CCQ43056 EAX04811 EAX04812 Q9BQ16 AB056866 BAB64908 AJ001454 CAA04775 AK091078 BAG52279 AK294293 BAG57576 AK294346 BAG57615 AK294637 BAG57816 AK295015 BAG58075 AK295281 BAG58265 AK295407 BAG58358 AK295414 BAG58364 AK296291 BAG58995 AK313042 BAG35874 AY358973 AAQ89332 BC000460 AAH00460 BC003017 AAH03017 BC013983 AAH13983 BI603782 DN989433 HQ447688 ADQ32173 XM_011532018 XP_011530320 NM_001040159 NP_001035249 NM_001204352 NP_001191281 NM_001204353 NP_001191282 NM_001204354 NP_001191283 NM_001204355 NP_001191284 NM_001204356 NP_001191285 NM_001204358 NP_001191287 NM_001251967 NP_001238896 NM_016950 NP_058646 NM_001204359 |
Function | May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in brain. |
Testican-3 CRISPR/Cas9 KO Plasmid (h) - sc-416889 from Santa Cruz Biotechnology
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Testican-3 HDR Plasmid (h) - sc-416889-HDR from Santa Cruz Biotechnology
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Testican-3 Double Nickase Plasmid (h) - sc-416889-NIC from Santa Cruz Biotechnology
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Testican-3 Double Nickase Plasmid (h2) - sc-416889-NIC-2 from Santa Cruz Biotechnology
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Testican-3 CRISPR Activation Plasmid (h) - sc-416889-ACT from Santa Cruz Biotechnology
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Testican-3 CRISPR Activation Plasmid (h2) - sc-416889-ACT-2 from Santa Cruz Biotechnology
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Testican-3 Lentiviral Activation Particles (h) - sc-416889-LAC from Santa Cruz Biotechnology
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Testican-3 Lentiviral Activation Particles (h2) - sc-416889-LAC-2 from Santa Cruz Biotechnology
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Testican-3 siRNA (h) - sc-61673 from Santa Cruz Biotechnology
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Testican-3 shRNA Plasmid (h) - sc-61673-SH from Santa Cruz Biotechnology
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Testican-3 shRNA (h) Lentiviral Particles - sc-61673-V from Santa Cruz Biotechnology
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Testican 3/SPOCK3 RNAi - H00050859-R01 from Novus Biologicals
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MISSION® esiRNA - EHU060281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20504 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20504 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09661 from Sigma-Aldrich
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SPOCK3 siRNA (Human) - CRH9429 from Cohesion Biosciences
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SPOCK3 - MBS8208063 from MyBioSource
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shRNA set against Human SPOCK3 (NM_016950.2) - SHH417052 from Creative biogene
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shRNA set against Human SPOCK3(NM_001040159.1) - SHL029946 from Creative biogene
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shRNA set against Human SPOCK3(NM_016950.2) - SHL030024 from Creative biogene
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Human SPOCK3 siRNA - orb269931 from Biorbyt
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SPOCK3 shRNA Plasmid (Human) - CHH9429 from Cohesion Biosciences
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SPOCK3 miRNA 3'UTR clone - MiUTR1H-09859 from Creative biogene
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SPOCK3 miRNA 3'UTR clone - MiUTR1H-09860 from Creative biogene
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