Gene Symbol | SPSB4 |
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Entrez Gene | 92369 |
Alt Symbol | SSB-4, SSB4 |
Species | Human |
Gene Type | protein-coding |
Description | splA/ryanodine receptor domain and SOCS box containing 4 |
Other Description | SPRY domain-containing SOCS box protein 4|SPRY domain-containing SOCS box protein SSB-4 |
Swissprots | Q96A44 |
Accessions | EAW79010 Q96A44 AF086345 AF403029 AAL57348 AK056147 AK056367 BAB71165 BC008324 AAH08324 BC051354 BX376865 CN366621 JF432868 ADZ16085 XM_011513313 XP_011511615 XR_924215 XR_924216 NM_080862 NP_543138 |
Function | Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:15601820}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
SSB-4 CRISPR/Cas9 KO Plasmid (h) - sc-413942 from Santa Cruz Biotechnology
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SSB-4 HDR Plasmid (h) - sc-413942-HDR from Santa Cruz Biotechnology
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SSB-4 Double Nickase Plasmid (h) - sc-413942-NIC from Santa Cruz Biotechnology
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SSB-4 Double Nickase Plasmid (h2) - sc-413942-NIC-2 from Santa Cruz Biotechnology
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SSB-4 CRISPR Activation Plasmid (h) - sc-413942-ACT from Santa Cruz Biotechnology
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SSB-4 CRISPR Activation Plasmid (h2) - sc-413942-ACT-2 from Santa Cruz Biotechnology
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SSB-4 Lentiviral Activation Particles (h) - sc-413942-LAC from Santa Cruz Biotechnology
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SSB-4 Lentiviral Activation Particles (h2) - sc-413942-LAC-2 from Santa Cruz Biotechnology
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SSB-4 siRNA (h) - sc-78045 from Santa Cruz Biotechnology
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SSB-4 shRNA Plasmid (h) - sc-78045-SH from Santa Cruz Biotechnology
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SSB-4 shRNA (h) Lentiviral Particles - sc-78045-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU151091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20538 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20538 from Sigma-Aldrich
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SPSB4 siRNA (Human) - CRJ4137 from Cohesion Biosciences
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SPSB4 - MBS8223441 from MyBioSource
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shRNA set against Human SPSB4 (NM_080862.1) - SHH417460 from Creative biogene
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shRNA set against Human SPSB4(NM_080862.1) - SHL030870 from Creative biogene
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SPSB4 shRNA Plasmid (Human) - CHJ4137 from Cohesion Biosciences
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SPSB4 miRNA 3'UTR clone - MiUTR1H-09882 from Creative biogene
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