Gene Symbol |
TADA2A
|
Entrez Gene |
6871
|
Alt Symbol |
ADA2, ADA2A, KL04P, TADA2L, hADA2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
transcriptional adaptor 2A
|
Other Description |
ADA2-like protein|transcriptional adapter 2-alpha|transcriptional adaptor 2 alpha
|
Swissprots |
Q9BVJ0 Q9UP49 Q9UCW2 O75478 A8MVD0 B3KMU9
|
Accessions |
AAB50689 EAW57587 EAW57588 EAW57589 EAW57590 EAW57591 O75478 AF064094 AAC26659 AF069732 AAC39902 AK022767 BAG51111 AK096371 BAG53275 AK225918 AL526501 BC001172 AAH01172 BC011753 AAH11753 BM470857 CD101741 DA244842 HQ447689 ADQ32174 XM_006722043 XP_006722106 XM_006722044 XP_006722107 XM_006725336 XP_006725399 XM_006725337 XP_006725400 XM_006725338 XP_006725401 XM_006725339 XP_006725402 XM_011525153 XP_011523455 XM_011525154 XP_011523456 XM_011525155 XP_011523457 XM_011525156 XP_011523458 XM_011525157 XP_011523459 XR_934539 XR_951960 NM_001166105 NP_001159577 NM_001291918 NP_001278847 NM_001488 NP_001479 NM_133439 NP_597683
|
Function |
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. {ECO:0000250, ECO:0000269|PubMed:19103755}.
|
Subcellular Location |
Nucleus. Chromosome.
|
Tissue Specificity |
Expressed in all tissues, but most abundantly in testis.
|