Gene Symbol | CYC1 |
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Entrez Gene | 1537 |
Alt Symbol | MC3DN6, UQCR4 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c-1 |
Other Description | complex III subunit 4|complex III subunit IV|cytochrome b-c1 complex subunit 4|cytochrome c1, heme protein, mitochondrial|ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit |
Swissprots | Q5U062 Q6FHS7 P08574 |
Accessions | AAA52135 ABB96244 EAW82160 P08574 AK026633 AK225796 BC001006 AAH01006 BC015616 AAH15616 BC020566 AAH20566 BC024650 AAH24650 BE336714 BG328536 BQ574597 BT019798 AAV38601 CN369438 CR541674 CAG46475 CR735564 DQ891486 ABM82412 DQ894671 ABM85597 M16597 AAA35730 X06994 CAA30052 NM_001916 NP_001907 |
Function | This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
cytochrome c1 CRISPR/Cas9 KO Plasmid (h) - sc-404958 from Santa Cruz Biotechnology
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cytochrome c1 HDR Plasmid (h) - sc-404958-HDR from Santa Cruz Biotechnology
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cytochrome c1 Double Nickase Plasmid (h) - sc-404958-NIC from Santa Cruz Biotechnology
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cytochrome c1 Double Nickase Plasmid (h2) - sc-404958-NIC-2 from Santa Cruz Biotechnology
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cytochrome c1 CRISPR Activation Plasmid (h) - sc-404958-ACT from Santa Cruz Biotechnology
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cytochrome c1 CRISPR Activation Plasmid (h2) - sc-404958-ACT-2 from Santa Cruz Biotechnology
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cytochrome c1 Lentiviral Activation Particles (h) - sc-404958-LAC from Santa Cruz Biotechnology
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cytochrome c1 Lentiviral Activation Particles (h2) - sc-404958-LAC-2 from Santa Cruz Biotechnology
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cytochrome c1 siRNA (h) - sc-77573 from Santa Cruz Biotechnology
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cytochrome c1 shRNA Plasmid (h) - sc-77573-SH from Santa Cruz Biotechnology
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cytochrome c1 shRNA (h) Lentiviral Particles - sc-77573-V from Santa Cruz Biotechnology
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CYC1 RNAi - H00001537-R01 from Novus Biologicals
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MISSION® esiRNA - EHU136111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6859 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6859 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01054 from Sigma-Aldrich
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CYC1 siRNA (Human) - CRH1086 from Cohesion Biosciences
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CYC1 - MBS8214903 from MyBioSource
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shRNA set against Human CYC1 (NM_001916.3) - SHH272685 from Creative biogene
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shRNA set against Human CYC1(NM_001916.3) - SHG214849 from Creative biogene
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Human CYC1 siRNA - orb261588 from Biorbyt
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CYC1 shRNA Plasmid (Human) - CHH1086 from Cohesion Biosciences
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CYC1 miRNA 3'UTR clone - MiUTR1H-02597 from Creative biogene
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