Gene Symbol | ANKS1B |
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Entrez Gene | 56899 |
Alt Symbol | AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat and sterile alpha motif domain containing 1B |
Other Description | E2a-Pbx1-associated protein|amyloid-beta precursor protein intracellular domain associated protein 1|ankyrin repeat and sterile alpha motif domain-containing protein 1B|cajalin 2 |
Swissprots | F8WC27 Q5XLJ0 Q7Z6G6 B4DFP6 B4DH98 Q7Z6G7 Q6IVB5 Q7Z6G8 A5PKY5 A8K153 F8VPM3 A8MSN4 Q9Y5K9 Q6NUS4 A7E259 Q8TAP3 Q9NRX7 F8VZR9 |
Accessions | Q7Z6G8 AF145204 AAD33951 AF164792 AAF80756 AK124453 AK289768 BAF82457 AK294191 BAG57507 AK294994 BAG58059 AK295988 BAG58763 AK315954 BAH14325 AM980945 CAQ37746 AY281131 AAP37612 AY281132 AAP37613 AY283057 AAP38184 AY356353 AAQ56189 AY620824 AAT39519 AY753193 AAV28691 BC026313 AAH26313 BC068451 AAH68451 BC091512 BC142669 AAI42670 BC150204 AAI50205 BC160005 AAI60005 BG338019 BP193713 BQ614098 BU568171 D80328 DA183756 DA690060 DA783474 DB475766 XM_005269028 XP_005269085 XM_005269029 XP_005269086 XM_005269032 XP_005269089 XM_006719504 XP_006719567 XM_006719505 XP_006719568 XM_006719506 XP_006719569 XM_006719507 XP_006719570 XM_006719508 XP_006719571 XM_006719509 XP_006719572 XM_006719510 XP_006719573 XM_006719511 XP_006719574 XM_006719512 XP_006719575 XM_006719513 XP_006719576 XM_006719514 XP_006719577 XM_011538570 XP_011536872 XM_011538571 XP_011536873 XM_011538572 XP_011536874 XR_944628 XR_944629 NM_001204065 NP_001190994 NM_001204066 NP_001190995 NM_001204067 NP_001190996 NM_001204068 NP_001190997 NM_001204069 NP_001190998 NM_001204070 NP_001190999 NM_001204079 NP_001191008 NM_001204080 NP_001191009 NM_001204081 NP_001191010 NM_020140 NP_064525 NM_152788 NP_690001 NM_181670 NP_858056 |
Function | Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing. |
Subcellular Location | Isoform 6: Nucleus. |
Tissue Specificity | Highly expressed in marrow from patients with pre-B ALL associated with the t(1;19) translocation. Strongly expressed in brain and testis. Expressed in fetal brain. Isoform 4 is highly expressed in brain (at protein level). Isoform 6 is expressed in brain and several cancer cell lines. {ECO:0000269|PubMed:10490826, ECO:0000269|PubMed:15347684}. |
AIDA-1 CRISPR/Cas9 KO Plasmid (h) - sc-404523 from Santa Cruz Biotechnology
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AIDA-1 HDR Plasmid (h) - sc-404523-HDR from Santa Cruz Biotechnology
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AIDA-1 Double Nickase Plasmid (h) - sc-404523-NIC from Santa Cruz Biotechnology
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AIDA-1 Double Nickase Plasmid (h2) - sc-404523-NIC-2 from Santa Cruz Biotechnology
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AIDA-1 CRISPR Activation Plasmid (h) - sc-404523-ACT from Santa Cruz Biotechnology
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AIDA-1 CRISPR Activation Plasmid (h2) - sc-404523-ACT-2 from Santa Cruz Biotechnology
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AIDA-1 Lentiviral Activation Particles (h) - sc-404523-LAC from Santa Cruz Biotechnology
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AIDA-1 Lentiviral Activation Particles (h2) - sc-404523-LAC-2 from Santa Cruz Biotechnology
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AIDA-1 siRNA (h) - sc-60141 from Santa Cruz Biotechnology
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AIDA-1 shRNA Plasmid (h) - sc-60141-SH from Santa Cruz Biotechnology
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AIDA-1 shRNA (h) Lentiviral Particles - sc-60141-V from Santa Cruz Biotechnology
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AIDA RNAi - H00064853-R02 from Novus Biologicals
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AIDA RNAi - H00064853-R01 from Novus Biologicals
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MISSION® esiRNA - EHU100081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3234 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3234 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01875 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09581 from Sigma-Aldrich
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ANKS1B siRNA (Human) - CRJ1205 from Cohesion Biosciences
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ANKS1B - MBS8212104 from MyBioSource
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shRNA set against Human Anks1 (NM_020140.3) - SHH237198 from Creative biogene
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ANKS1B shRNA Plasmid (Human) - CHJ1205 from Cohesion Biosciences
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ANKS1B miRNA 3'UTR clone - MiUTR3H-09482 from Creative biogene
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ANKS1B miRNA 3'UTR clone - MiUTR3H-09483 from Creative biogene
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ANKS1B miRNA 3'UTR clone - MiUTR3H-09484 from Creative biogene
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