| Gene Symbol |
DUSP13
|
| Entrez Gene |
51207
|
| Alt Symbol |
BEDP, DUSP13A, DUSP13B, MDSP, SKRP4, TMDP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dual specificity phosphatase 13
|
| Other Description |
branching-enzyme interacting DSP|branching-enzyme interacting dual-specificity protein phosphatase|dual specificity protein phosphatase 13|muscle-restricted DSP|testis- and skeletal-muscle-specific DSP
|
| Swissprots |
A8K776 Q9UII6 Q96J67 Q6B8I1 A8K782 Q5JSC6 B4DUK0 Q96GC2 Q6IAR0 B3KPY1 B3KXT0
|
| Accessions |
EAW54561 EAW54562 EAW54563 EAW54564 Q6B8I1 Q9UII6 AB027004 BAA89412 AB103375 BAD91014 AI971328 AK057012 BAG51843 AK127886 BAG54592 AK291891 BAF84580 AK291897 BAF84586 AK300679 BAG62362 AY040091 AAK77966 AY674051 AAT79356 BC009778 AAH09778 BU580940 CR457094 CAG33375 DQ892732 ABM83658 DQ895979 ABM86905 XM_005269883 XP_005269940 XM_005269884 XP_005269941 XM_005269886 XP_005269943 XM_005269887 XP_005269944 XM_005269888 XP_005269945 XM_005269890 XP_005269947 XM_011539853 XP_011538155 XM_011539854 XP_011538156 XM_011539855 XP_011538157 XM_011539856 XP_011538158 NM_001007271 NP_001007272 NM_001007272 NP_001007273 NM_001007273 NP_001007274 NM_016364 NP_057448 NM_001007274 NM_001007275
|
| Function |
Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro. {ECO:0000269|PubMed:21360282}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15252030}.
|
| Tissue Specificity |
Most abundantly expressed in the testis. Also found in the skeletal muscle. Testis-specific (at protein level). {ECO:0000269|PubMed:15252030}.
|
![Western Blot: DUSP13 Overexpression Lysate (Adult Normal) [NBP2-07039] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DUSP13.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/18095_DUSP13%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-07039-img0001.jpg)