Gene Symbol | CTNNBL1 |
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Entrez Gene | 56259 |
Alt Symbol | C20orf33, NAP, P14L, PP8304, dJ633O20.1 |
Species | Human |
Gene Type | protein-coding |
Description | catenin, beta like 1 |
Other Description | beta-catenin-like protein 1|nuclear associated protein|testis development protein NYD-SP19 |
Swissprots | Q5JWZ3 Q9H7A5 Q8N454 Q5JWZ7 Q5JWZ8 Q5JWZ2 Q9NQF9 Q53HI8 Q96KD2 Q8TBD6 Q9Y3M7 Q9NTX0 Q8WYA6 B4DE16 Q8NCL2 Q0VAL9 Q0VAM0 |
Accessions | EAW76054 EAW76055 Q8WYA6 AA469176 AF086002 AF239607 AAL69567 AF367471 AAK53407 AF370431 AAQ15267 AK024761 BAB14992 AK074663 BAC11121 AK091216 AK130301 AK222592 BAD96312 AK293420 BAG56927 BC022802 AAH22802 BC036739 BC121005 AAI21006 BC121006 AAI21007 CB137946 DC358260 XM_011528917 XP_011527219 NM_001281495 NP_001268424 NM_030877 NP_110517 |
Function | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. |
Subcellular Location | Isoform 1: Nucleus. |
Tissue Specificity | Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid. {ECO:0000269|PubMed:12659813}. |
Top Pathways | Spliceosome |
CTNNBL1 CRISPR/Cas9 KO Plasmid (h) - sc-409293 from Santa Cruz Biotechnology
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CTNNBL1 HDR Plasmid (h) - sc-409293-HDR from Santa Cruz Biotechnology
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CTNNBL1 Double Nickase Plasmid (h) - sc-409293-NIC from Santa Cruz Biotechnology
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CTNNBL1 Double Nickase Plasmid (h2) - sc-409293-NIC-2 from Santa Cruz Biotechnology
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CTNNBL1 CRISPR Activation Plasmid (h) - sc-409293-ACT from Santa Cruz Biotechnology
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CTNNBL1 CRISPR Activation Plasmid (h2) - sc-409293-ACT-2 from Santa Cruz Biotechnology
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CTNNBL1 Lentiviral Activation Particles (h) - sc-409293-LAC from Santa Cruz Biotechnology
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CTNNBL1 Lentiviral Activation Particles (h2) - sc-409293-LAC-2 from Santa Cruz Biotechnology
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CTNNBL1 siRNA (h) - sc-77045 from Santa Cruz Biotechnology
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CTNNBL1 shRNA Plasmid (h) - sc-77045-SH from Santa Cruz Biotechnology
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CTNNBL1 shRNA (h) Lentiviral Particles - sc-77045-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU115271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6738 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6738 from Sigma-Aldrich
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CTNNBL1 siRNA (Human) - CRJ1121 from Cohesion Biosciences
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CTNNBL1 RNAi - H00056259-R01 from Novus Biologicals
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CTNNBL1 - MBS8222976 from MyBioSource
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shRNA set against Human CTNNBL1 (NM_030877.3) - SHH271333 from Creative biogene
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shRNA set against Human CTNNBL1(NM_030877.3) - SHG171901 from Creative biogene
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Human CTNNBL1 siRNA - orb271622 from Biorbyt
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CTNNBL1 shRNA Plasmid (Human) - CHJ1121 from Cohesion Biosciences
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CTNNBL1 miRNA 3'UTR clone - MiUTR1H-02530 from Creative biogene
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