| Gene Symbol |
IFNE
|
| Entrez Gene |
338376
|
| Alt Symbol |
IFN-E, IFNE1, IFNT1, INFE1, PRO655
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interferon, epsilon
|
| Other Description |
IFN-epsilon|interferon epsilon|interferon epsilon 1|interferon epsilon-1|interferon tau-1|interferon-epsilon
|
| Swissprots |
Q86WN2
|
| Accessions |
Q86WN2 AY190045 AAO38686 AY358570 AAQ88933 BC100871 AAI00872 BC100872 AAI00873 BC100873 AAI00874 NM_176891 NP_795372
|
| Function |
Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|
| Tissue Specificity |
Endometrium-specific. {ECO:0000269|PubMed:23449591}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway
|