Gene Symbol | PDE6B |
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Entrez Gene | 5158 |
Alt Symbol | CSNB3, CSNBAD2, PDEB, RP40, rd1 |
Species | Human |
Gene Type | protein-coding |
Description | phosphodiesterase 6B, cGMP-specific, rod, beta |
Other Description | GMP-PDE beta|rod cGMP-phosphodiesterase beta-subunit|rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta |
Swissprots | Q9BWH5 E7ETT3 Q53XN5 B7Z9T9 Q9UD49 P35913 |
Accessions | AAB00387 AAD14270 CAA44569 CAA44570 CAA44571 CAA62215 EAW82661 EAW82662 P35913 AI131517 AK295285 BAG58269 AK308789 AK309252 AK316054 BAH14425 BC000249 AAH00249 BC039412 BT009794 AAP88796 BX487988 DQ895767 ABM86693 EU176360 ABW03811 FJ417399 S41458 AAB22690 X66142 CAA46932 XM_011513473 XP_011511775 XM_011513474 XP_011511776 XM_011513475 XP_011511777 XM_011513476 XP_011511778 XM_011513477 XP_011511779 XM_011513478 XP_011511780 NM_000283 NP_000274 NM_001145291 NP_001138763 NM_001145292 NP_001138764 |
Function | This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme. |
Subcellular Location | Membrane; Lipid-anchor. |
Top Pathways | Phototransduction, Purine metabolism |
PDE6β siRNA (h) - sc-106850 from Santa Cruz Biotechnology
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PDE6β shRNA Plasmid (h) - sc-106850-SH from Santa Cruz Biotechnology
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PDE6β shRNA (h) Lentiviral Particles - sc-106850-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU044031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1672 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1672 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05685 from Sigma-Aldrich
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PDE6B siRNA (Human) - CRH3438 from Cohesion Biosciences
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shRNA set against Human PDE6B (NM_000283.3) - SHH372512 from Creative biogene
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Human PDE6B siRNA - orb263940 from Biorbyt
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PDE6B shRNA Plasmid (Human) - CHH3438 from Cohesion Biosciences
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PDE6B miRNA 3'UTR clone - MiUTR3H-02017 from Creative biogene
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PDE6B miRNA 3'UTR clone - MiUTR3H-02018 from Creative biogene
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PDE6B miRNA 3'UTR clone - MiUTR3H-02019 from Creative biogene
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